Overexpression of Membrane-bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-induced Lupus

Loss of function mutations in the Fas death receptor or its ligand result in a lymphoproliferative syndrome and exacerbate clinical disease in most lupus-prone strains of mice. One exception is mice injected with 2,6,10,14-Tetramethylpentadecane (TMPD), a hydrocarbon oil commonly known as pristane,...

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Bossaller, Lukas, Rathinam, Vijay A.K., Bonegio, Ramon, Chiang, Ping-I, Busto, Patricia, Wespiser, Adam R., Caffrey, Daniel R., Li, Quan-Zhen, Mohan, Chandra, Fitzgerald, Katherine A., Latz, Eicke, Marshak-Rothstein, Ann
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219920/
https://ncbi.nlm.nih.gov/pubmed/23918976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300341
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items