Inflammation in Mice Ectopically Expressing Human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T Mutant Proteins

Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne Syndrome (PAPA syndrome) is an autoinflammatory disease caused by aberrant production of the proinflammatory cytokine interleukin-1. Mutations in the gene encoding proline serine threonine phosphatase-interacting protein-1 (PSTPIP1) have been linked...

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Main Authors: Wang, Donghai, Höing, Susanne, Patterson, Heide Christine, Ahmad, Umtul M., Rathinam, Vijay A. K., Rajewsky, Klaus, Fitzgerald, Katherine A., Golenbock, Douglas T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576065/
https://ncbi.nlm.nih.gov/pubmed/23293022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443077
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