TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

Systemic infections with Gram-negative bacteria are characterized by high mortality rates due to the “sepsis syndrome,” a widespread and uncontrolled inflammatory response. Though it is well recognized that the immune response during Gram-negative bacterial infection is initiated after the recogniti...

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Bibliographic Details
Main Authors: Rathinam, Vijay A.K., Vanaja, Sivapriya Kailasan, Waggoner, Lisa, Sokolovska, Anna, Becker, Christine, Stuart, Lynda M., Leong, John M., Fitzgerald, Katherine A.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660860/
https://ncbi.nlm.nih.gov/pubmed/22819539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.07.007
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