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Mechanisms of inflammasome activation: recent advances and novel insights

Inflammasomes are cytosolic multiprotein platforms assembled in response to invading pathogens and other danger signals. Typically inflammasome complexes contain a sensor protein, an adaptor protein and a zymogen, procaspase-1. Formation of inflammasome assembly results in processing of inactive pro...

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Bibliografiske detaljer
Udgivet i:Trends Cell Biol
Main Authors: Vanaja, Sivapriya, Rathinam, Vijay K., Fitzgerald, Katherine A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409512/
https://ncbi.nlm.nih.gov/pubmed/25639489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.12.009
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