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Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation

Inflammasomes are high-molecular-weight protein complexes that are formed in the cytosolic compartment in response to danger- or pathogen-associated molecular patterns. These complexes enable activation of an inflammatory protease caspase-1, leading to a cell death process called pyroptosis and to p...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Próchnicki, Tomasz, Mangan, Matthew S., Latz, Eicke
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963208/
https://ncbi.nlm.nih.gov/pubmed/27508077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.8614.1
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