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New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease
Inflammasomes are large macromolecular signaling complexes that control the proteolytic activation of two highly proinflammatory IL-1 family cytokines, IL-1β and IL-18. The NLRP3 inflammasome is of special interest because it can assemble in response to a diverse array of stimuli and because the inf...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873477/ https://ncbi.nlm.nih.gov/pubmed/24183846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.09.007 |
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