Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency

Lysine (K) type cationic lipid with a propyl spacer and ditetradecyl hydrophobic moieties composing liposomes, K3C14, previously studied for gene delivery, were reported to activate the NLRP3 inflammasomes in human macrophages via the conventional phagolysosomal pathway. In this study, K3C16, a prop...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biochem Biophys Rep
Autori principali: He, Jieyan, Li, Tianshu, Próchnicki, Tomasz, Horvath, Gabor, Latz, Eicke, Takeoka, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462779/
https://ncbi.nlm.nih.gov/pubmed/31011633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100623
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi