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Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency
Lysine (K) type cationic lipid with a propyl spacer and ditetradecyl hydrophobic moieties composing liposomes, K3C14, previously studied for gene delivery, were reported to activate the NLRP3 inflammasomes in human macrophages via the conventional phagolysosomal pathway. In this study, K3C16, a prop...
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| 出版年: | Biochem Biophys Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462779/ https://ncbi.nlm.nih.gov/pubmed/31011633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100623 |
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