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Inflammasome complexes: emerging mechanisms and effector functions
Canonical activation of the inflammasome is critical to promote caspase-1-dependent maturation of the proinflammatory cytokines IL-1β and IL-18, as well as to induce pyroptotic cell death in response to pathogens and endogenous danger signals. Recent discoveries, however, are beginning to unveil new...
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| Publicado no: | Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5503689/ https://ncbi.nlm.nih.gov/pubmed/27153493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.046 |
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