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Inflammasome complexes: emerging mechanisms and effector functions

Canonical activation of the inflammasome is critical to promote caspase-1-dependent maturation of the proinflammatory cytokines IL-1β and IL-18, as well as to induce pyroptotic cell death in response to pathogens and endogenous danger signals. Recent discoveries, however, are beginning to unveil new...

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Publicat a:Cell
Autors principals: Rathinam, Vijay A. K., Fitzgerald, Katherine A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503689/
https://ncbi.nlm.nih.gov/pubmed/27153493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.046
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