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Aim2-deficiency in mice suppresses the expression of the inhibitory Fcγ receptor (FcγRIIB) through the induction of the interferon-inducible p202, a lupus susceptibility protein
Murine Aim2 and Ifi202 genes (encoding for the Aim2 and p202 proteins) are members of the interferon (IFN)-inducible Ifi200-gene family. The Aim2-deficiency in mice activates IFN-signaling and stimulates the expression of lupus susceptibility gene, the Ifi202, located within the Nba2 interval. Given...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110550/ https://ncbi.nlm.nih.gov/pubmed/21551362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003638 |
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