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Stimulation of T cells up-regulates expression of Ifi202, an interferon-inducible lupus susceptibility gene, through activation of JNK/c-Jun pathway

Studies have revealed that increased expression of interferon (IFN)-inducible Ifi202 gene (encoding p202 protein) in splenic B and T cells from B6.Nba2 congenic (congenic for Nb2 locus derived from NZB mice) female mice is associated with lupus susceptibility. However, signaling pathways that regula...

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Detalhes bibliográficos
Main Authors: Chen, Jianming, Panchanathan, Ravichandran, Choubey, Divaker
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504419/
https://ncbi.nlm.nih.gov/pubmed/18374989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2008.02.005
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