Searching for the Chokehold of NRAS Mutant Melanoma

Por Posch, Christian, Vujic, Igor, Monshi, Babak, Sanlorenzo, Martina, Weihsengruber, Felix, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no J Invest Dermatol (2016)

The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines

Por Valiahdi, Seied Mojtaba, Heffeter, Petra, Jakupec, Michael A., Marculescu, Rodrig, Berger, Walter, Rappersberger, Klemens, Keppler, Bernhard K.
Publicado em 2009

Pharmacological inhibitors of c-KIT block mutant c-KIT mediated migration of melanocytes and melanoma cells in vitro and in vivo

Por Posch, Christian, Moslehi, Homayoun, Sanlorenzo, Martina, Green, Gary, Vujic, Igor, Panzer-Grümayer, Renate, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no Oncotarget (2016)

Neutrophil Granulocyte–committed Cells Can Be Driven to Acquire Dendritic Cell Characteristics

Por Oehler, Leopold, Majdic, Otto, Pickl, Winfried F., Stöckl, Johannes, Riedl, Elisabeth, Drach, Johannes, Rappersberger, Klemens, Geissler, Klaus, Knapp, Walter
Publicado em 1998

Pembrolizumab Cutaneous Adverse Events and Their Association With Disease Progression

Por Sanlorenzo, Martina, Vujic, Igor, Daud, Adil, Algazi, Alain, Gubens, Matthew, Luna, Sara Alcántara, Lin, Kevin, Quaglino, Pietro, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no JAMA Dermatol (2015)

Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer

Por Vujic, Igor, Sanlorenzo, Martina, Posch, Christian, Esteve-Puig, Rosaura, Yen, Adam J., Kwong, Andrew, Tsumura, Aaron, Murphy, Ryan, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no Oncotarget (2014)

Mutant NRAS(Q61) shares signaling similarities across various cancer types – potential implications for future therapies

Por Vujic, Igor, Posch, Christian, Sanlorenzo, Martina, Yen, Adam J., Tsumura, Aaron, Kwong, Andrew, Feichtenschlager, Valentin, Lai, Kevin, Arneson, Douglas V., Rappersberger, Klemens, Ortiz-Urda, Susana M.
Publicado em 2014

Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells

Por Vujic, Igor, Sanlorenzo, Martina, Esteve-Puig, Rosaura, Vujic, Marin, Kwong, Andrew, Tsumura, Aaron, Murphy, Ryan, Moy, Adrian, Posch, Christian, Monshi, Babak, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no Oncotarget (2016)

Comparative profile of cutaneous adverse events: BRAF/MEK inhibitor combination therapy versus BRAF monotherapy in melanoma

Por Sanlorenzo, Martina, Choudhry, Aditi, Vujic, Igor, Posch, Christian, Chong, Kim, Johnston, Katia, Meier, Melissa, Osella-Abate, Simona, Quaglino, Pietro, Daud, Adil, Algazi, Alain, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no J Am Acad Dermatol (2014)

Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles

Por Posch, Christian, Latorre, Alfonso, Crosby, Michelle B., Celli, Anna, Latorre, Ana, Vujic, Igor, Sanlorenzo, Martina, Green, Gary A., Weier, Jingly, Zekhtser, Mitchell, Ma, Jeffrey, Monico, Gabriela, Char, Devron H., Jusufbegovic, Denis, Rappersberger, Klemens, Somoza, Álvaro, Ortiz-Urda, Susana
Publicado no Biomed Microdevices (2015)

Phosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells

Por Posch, Christian, Sanlorenzo, Martina, Vujic, Igor, Oses-Prieto, Juan A., Cholewa, Brian D., Kim, Sarasa T., Ma, Jeffrey, Lai, Kevin, Zekhtser, Mitchell, Esteve-Puig, Rosaura, Green, Gary, Chand, Shreya, Burlingame, Alma L., Panzer-Grümayer, Renate, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no J Invest Dermatol (2016)

The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma

Por Sanlorenzo, Martina, Vujic, Igor, Esteve-Puig, Rosaura, Lai, Kevin, Vujic, Marin, Lin, Kevin, Posch, Christian, Dimon, Michelle, Moy, Adrian, Zekhtser, Mitchell, Johnston, Katia, Gho, Deborah, Ho, Wilson, Gajjala, Abhinay, Oses Prieto, Juan, Burlingame, Alma, Daud, Adil, Rappersberger, Klemens, Ortiz-Urda, Susana
Publicado no Sci Rep (2018)

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

Por Somasundaram, Rajasekharan, Zhang, Gao, Fukunaga-Kalabis, Mizuho, Perego, Michela, Krepler, Clemens, Xu, Xiaowei, Wagner, Christine, Hristova, Denitsa, Zhang, Jie, Tian, Tian, Wei, Zhi, Liu, Qin, Garg, Kanika, Griss, Johannes, Hards, Rufus, Maurer, Margarita, Hafner, Christine, Mayerhöfer, Marius, Karanikas, Georgios, Jalili, Ahmad, Bauer-Pohl, Verena, Weihsengruber, Felix, Rappersberger, Klemens, Koller, Josef, Lang, Roland, Hudgens, Courtney, Chen, Guo, Tetzlaff, Michael, Wu, Lawrence, Frederick, Dennie Tompers, Scolyer, Richard A., Long, Georgina V., Damle, Manashree, Ellingsworth, Courtney, Grinman, Leon, Choi, Harry, Gavin, Brian J., Dunagin, Margaret, Raj, Arjun, Scholler, Nathalie, Gross, Laura, Beqiri, Marilda, Bennett, Keiryn, Watson, Ian, Schaider, Helmut, Davies, Michael A., Wargo, Jennifer, Czerniecki, Brian J., Schuchter, Lynn, Herlyn, Dorothee, Flaherty, Keith, Herlyn, Meenhard, Wagner, Stephan N.
Publicado no Nat Commun (2017)