The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma

Despite major advances in targeted melanoma therapies, drug resistance limits their efficacy. Long noncoding RNAs (lncRNAs) are transcriptome elements that do not encode proteins but are important regulatory molecules. LncRNAs have been implicated in cancer development and response to different ther...

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Publicado no:Sci Rep
Main Authors: Sanlorenzo, Martina, Vujic, Igor, Esteve-Puig, Rosaura, Lai, Kevin, Vujic, Marin, Lin, Kevin, Posch, Christian, Dimon, Michelle, Moy, Adrian, Zekhtser, Mitchell, Johnston, Katia, Gho, Deborah, Ho, Wilson, Gajjala, Abhinay, Oses Prieto, Juan, Burlingame, Alma, Daud, Adil, Rappersberger, Klemens, Ortiz-Urda, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053443/
https://ncbi.nlm.nih.gov/pubmed/30026510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27643-3
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