Mutant NRAS(Q61) shares signaling similarities across various cancer types – potential implications for future therapies

Oncogenic mutations in the Neuroblastoma Rat Sarcoma oncogene (NRAS) are frequent in melanoma, but are also found in several other cancer types, such as lung cancer, neuroblastoma and colon cancer. We designed our study to analyze changes in NRAS mutant tumor cells derived from malignancies other th...

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Bibliographic Details
Main Authors: Vujic, Igor, Posch, Christian, Sanlorenzo, Martina, Yen, Adam J., Tsumura, Aaron, Kwong, Andrew, Feichtenschlager, Valentin, Lai, Kevin, Arneson, Douglas V., Rappersberger, Klemens, Ortiz-Urda, Susana M.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202171/
https://ncbi.nlm.nih.gov/pubmed/25277205
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