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Mutant NRAS(Q61) shares signaling similarities across various cancer types – potential implications for future therapies

Oncogenic mutations in the Neuroblastoma Rat Sarcoma oncogene (NRAS) are frequent in melanoma, but are also found in several other cancer types, such as lung cancer, neuroblastoma and colon cancer. We designed our study to analyze changes in NRAS mutant tumor cells derived from malignancies other th...

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Main Authors: Vujic, Igor, Posch, Christian, Sanlorenzo, Martina, Yen, Adam J., Tsumura, Aaron, Kwong, Andrew, Feichtenschlager, Valentin, Lai, Kevin, Arneson, Douglas V., Rappersberger, Klemens, Ortiz-Urda, Susana M.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202171/
https://ncbi.nlm.nih.gov/pubmed/25277205
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