Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles

BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Early treatment may improve any chances of preventing metastatic disease, but diagnosis of small UM is challenging. Up to 95 % of all UMs carry somatic mutations in the G-coupled proteins GNAQ and GNA11 prom...

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保存先:
書誌詳細
出版年:Biomed Microdevices
主要な著者: Posch, Christian, Latorre, Alfonso, Crosby, Michelle B., Celli, Anna, Latorre, Ana, Vujic, Igor, Sanlorenzo, Martina, Green, Gary A., Weier, Jingly, Zekhtser, Mitchell, Ma, Jeffrey, Monico, Gabriela, Char, Devron H., Jusufbegovic, Denis, Rappersberger, Klemens, Somoza, Álvaro, Ortiz-Urda, Susana
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586106/
https://ncbi.nlm.nih.gov/pubmed/25653058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10544-014-9908-7
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