Site-selective Suzuki–Miyaura coupling of heteroaryl halides – understanding the trends for pharmaceutically important classes

nork Almond-Thynne, Joshua, Blakemore, David C., Pryde, David C., Spivey, Alan C.
Argitaratua izan da Chem Sci (2017)

G10 is a direct activator of human STING

nork Banerjee, Monali, Middya, Sandip, Shrivastava, Ritesh, Basu, Sourav, Ghosh, Rajib, Pryde, David C., Yadav, Dharmendra B., Surya, Arjun
Argitaratua izan da PLoS One (2020)

Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism

nork Bagnéris, Claire, DeCaen, Paul G., Naylor, Claire E., Pryde, David C., Nobeli, Irene, Clapham, David E., Wallace, B. A.
Argitaratua 2014

Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs

nork Tang, Lin, Gamal El-Din, Tamer M., Swanson, Teresa M., Pryde, David C., Scheuer, Todd, Zheng, Ning, Catterall, William A.
Argitaratua izan da Nature (2016)

Selection, Optimization, and Pharmacokinetic Properties of a Novel, Potent Antiviral Locked Nucleic Acid-Based Antisense Oligomer Targeting Hepatitis C Virus Internal Ribosome Entr...

nork Laxton, Carl, Brady, Kevin, Moschos, Sterghios, Turnpenny, Paul, Rawal, Jaiessh, Pryde, David C., Sidders, Ben, Corbau, Romu, Pickford, Chris, Murray, E. J.
Argitaratua 2011

TRPA1 ankyrin repeat six interacts with a small molecule inhibitor chemotype

nork Tseng, Wei Chou, Pryde, David C., Yoger, Katrina E., Padilla, Karen M., Antonio, Brett M., Han, Seungil, Shanmugasundaram, Veerabahu, Gerlach, Aaron C.
Argitaratua izan da Proc Natl Acad Sci U S A (2018)

Valproic acid interactions with the NavMs voltage-gated sodium channel

nork Zanatta, Geancarlo, Sula, Altin, Miles, Andrew J., Ng, Leo C. T., Torella, Rubben, Pryde, David C., DeCaen, Paul G., Wallace, B. A.
Argitaratua izan da Proc Natl Acad Sci U S A (2019)

Trypanosoma brucei Glycogen Synthase Kinase-3, A Target for Anti-Trypanosomal Drug Development: A Public-Private Partnership to Identify Novel Leads

nork Oduor, Richard O., Ojo, Kayode K., Williams, Gareth P., Bertelli, Francois, Mills, James, Maes, Louis, Pryde, David C., Parkinson, Tanya, Van Voorhis, Wesley C., Holler, Tod P.
Argitaratua 2011

Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain

nork Andrews, Mark D., af Forselles, Kerry, Beaumont, Kevin, Galan, Sébastien R. G., Glossop, Paul A., Grenie, Mathilde, Jessiman, Alan, Kenyon, Amy S., Lunn, Graham, Maw, Graham, Owen, Robert M., Pryde, David C., Roberts, Dannielle, Tran, Thien Duc
Argitaratua izan da ACS Med Chem Lett (2015)

Discovery of a Series of Indazole TRPA1 Antagonists

nork Pryde, David C., Marron, Brian E., West, Christopher W., Reister, Steven, Amato, George, Yoger, Katrina, Antonio, Brett, Padilla, Karen, Cox, Peter J., Turner, Jamie, Warmus, Joseph S., Swain, Nigel A., Omoto, Kiyoyuki, Mahoney, John H., Gerlach, Aaron C.
Argitaratua izan da ACS Med Chem Lett (2017)

A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation–π Interaction**

nork Rooney, Timothy P C, Filippakopoulos, Panagis, Fedorov, Oleg, Picaud, Sarah, Cortopassi, Wilian A, Hay, Duncan A, Martin, Sarah, Tumber, Anthony, Rogers, Catherine M, Philpott, Martin, Wang, Minghua, Thompson, Amber L, Heightman, Tom D, Pryde, David C, Cook, Andrew, Paton, Robert S, Müller, Susanne, Knapp, Stefan, Brennan, Paul E, Conway, Stuart J
Argitaratua izan da Angew Chem Int Ed Engl (2014)

A Pharmacological Master Key Mechanism that Unlocks the Selectivity Filter Gate in K(+) Channels

nork Schewe, Marcus, Sun, Han, Mert, Ümit, Mackenzie, Alexandra, Pike, Ashley C. W., Schulz, Friederike, Constantin, Cristina, Vowinkel, Kirsty S., Conrad, Linus J., Kiper, Aytug K., Gonzalez, Wendy, Musinszki, Marianne, Tegtmeier, Marie, Pryde, David C., Belabed, Hassane, Nazare, Marc, de Groot, Bert L., Decher, Niels, Fakler, Bernd, Carpenter, Elisabeth P., Tucker, Stephen J., Baukrowitz, Thomas
Argitaratua izan da Science (2019)

Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

nork Pryde, David C., Jones, Lyn H., Gervais, David P., Stead, David R., Blakemore, David C., Selby, Matthew D., Brown, Alan D., Coe, Jotham W., Badland, Matthew, Beal, David M., Glen, Rebecca, Wharton, Yvonne, Miller, Gavin J., White, Phil, Zhang, Ningli, Benoit, Michelle, Robertson, Karen, Merson, James R., Davis, Heather L., McCluskie, Michael J.
Argitaratua 2013

11th German Conference on Chemoinformatics (GCC 2015): Fulda, Germany. 8–10 November 2015

nork Fechner, Uli, de Graaf, Chris, Torda, Andrew E., Güssregen, Stefan, Evers, Andreas, Matter, Hans, Hessler, Gerhard, Richmond, Nicola J., Schmidtke, Peter, Segler, Marwin H. S., Waller, Mark P., Pleik, Stefanie, Shea, Joan-Emma, Levine, Zachary, Mullen, Ryan, van den Broek, Karina, Epple, Matthias, Kuhn, Hubert, Truszkowski, Andreas, Zielesny, Achim, Fraaije, Johannes (Hans), Gracia, Ruben Serral, Kast, Stefan M., Bulusu, Krishna C., Bender, Andreas, Yosipof, Abraham, Nahum, Oren, Senderowitz, Hanoch, Krotzky, Timo, Schulz, Robert, Wolber, Gerhard, Bietz, Stefan, Rarey, Matthias, Zimmermann, Markus O., Lange, Andreas, Ruff, Manuel, Heidrich, Johannes, Onlia, Ionut, Exner, Thomas E., Boeckler, Frank M., Bermudez, Marcel, Firaha, Dzmitry S., Hollóczki, Oldamur, Kirchner, Barbara, Tautermann, Christofer S., Volkamer, Andrea, Eid, Sameh, Turk, Samo, Rippmann, Friedrich, Fulle, Simone, Saleh, Noureldin, Saladino, Giorgio, Gervasio, Francesco L., Haensele, Elke, Banting, Lee, Whitley, David C., Oliveira Santos, Jana Sopkova-de, Bureau, Ronan, Clark, Timothy, Sandmann, Achim, Lanig, Harald, Kibies, Patrick, Heil, Jochen, Hoffgaard, Franziska, Frach, Roland, Engel, Julian, Smith, Steven, Basu, Debjit, Rauh, Daniel, Kohlbacher, Oliver, Boeckler, Frank M., Essex, Jonathan W., Bodnarchuk, Michael S., Ross, Gregory A., Finkelmann, Arndt R., Göller, Andreas H., Schneider, Gisbert, Husch, Tamara, Schütter, Christoph, Balducci, Andrea, Korth, Martin, Ntie-Kang, Fidele, Günther, Stefan, Sippl, Wolfgang, Mbaze, Luc Meva’a, Ntie-Kang, Fidele, Simoben, Conrad V., Lifongo, Lydia L., Ntie-Kang, Fidele, Judson, Philip, Barilla, Jiří, Lokajíček, Miloš V., Pisaková, Hana, Simr, Pavel, Kireeva, Natalia, Petrov, Alexandre, Ostroumov, Denis, Solovev, Vitaly P., Pervov, Vladislav S., Friedrich, Nils-Ole, Sommer, Kai, Rarey, Matthias, Kirchmair, Johannes, Proschak, Eugen, Weber, Julia, Moser, Daniel, Kalinowski, Lena, Achenbach, Janosch, Mackey, Mark, Cheeseright, Tim, Renner, Gerrit, Renner, Gerrit, Schmidt, Torsten C., Schram, Jürgen, Egelkraut-Holtus, Marion, van Oeyen, Albert, Kalliokoski, Tuomo, Fourches, Denis, Ibezim, Akachukwu, Mbah, Chika J., Adikwu, Umale M., Nwodo, Ngozi J., Steudle, Alexander, Masek, Brian B., Nagy, Stephan, Baker, David, Soltanshahi, Fred, Dorfman, Roman, Dubrucq, Karen, Patel, Hitesh, Koch, Oliver, Mrugalla, Florian, Kast, Stefan M., Ain, Qurrat U., Fuchs, Julian E., Owen, Robert M., Omoto, Kiyoyuki, Torella, Rubben, Pryde, David C., Glen, Robert, Bender, Andreas, Hošek, Petr, Spiwok, Vojtěch, Mervin, Lewis H., Barrett, Ian, Firth, Mike, Murray, David C., McWilliams, Lisa, Cao, Qing, Engkvist, Ola, Warszycki, Dawid, Śmieja, Marek, Bojarski, Andrzej J., Aniceto, Natalia, Freitas, Alex, Ghafourian, Taravat, Herrmann, Guido, Eigner-Pitto, Valentina, Naß, Alexandra, Kurczab, Rafał, Bojarski, Andrzej J., Lange, Andreas, Günther, Marcel B., Hennig, Susanne, Büttner, Felix M., Schall, Christoph, Sievers-Engler, Adrian, Ansideri, Francesco, Koch, Pierre, Stehle, Thilo, Laufer, Stefan, Böckler, Frank M., Zdrazil, Barbara, Montanari, Floriane, Ecker, Gerhard F., Grebner, Christoph, Hogner, Anders, Ulander, Johan, Edman, Karl, Guallar, Victor, Tyrchan, Christian, Ulander, Johan, Tyrchan, Christian, Klute, Wolfgang, Bergström, Fredrik, Kramer, Christian, Nguyen, Quoc Dat, Frach, Roland, Kibies, Patrick, Strohfeldt, Steven, Böttcher, Saraphina, Pongratz, Tim, Horinek, Dominik, Kast, Stefan M., Rupp, Bernd, Al-Yamori, Raed, Lisurek, Michael, Kühne, Ronald, Furtado, Filipe, van den Broek, Karina, Wessjohann, Ludger, Mathea, Miriam, Baumann, Knut, Mohamad-Zobir, Siti Zuraidah, Fu, Xianjun, Fan, Tai-Ping, Bender, Andreas, Kuhn, Maximilian A., Sotriffer, Christoph A., Zoufir, Azedine, Li, Xitong, Mervin, Lewis, Berg, Ellen, Polokoff, Mark, Ihlenfeldt, Wolf D., Ihlenfeldt, Wolf D., Pretzel, Jette, Alhalabi, Zayan, Fraczkiewicz, Robert, Waldman, Marvin, Clark, Robert D., Shaikh, Neem, Garg, Prabha, Kos, Alexander, Himmler, Hans-Jürgen, Sandmann, Achim, Jardin, Christophe, Sticht, Heinrich, Steinbrecher, Thomas B., Dahlgren, Markus, Cappel, Daniel, Lin, Teng, Wang, Lingle, Krilov, Goran, Abel, Robert, Friesner, Richard, Sherman, Woody, Pöhner, Ina A., Panecka, Joanna, Wade, Rebecca C., Bietz, Stefan, Schomburg, Karen T., Hilbig, Matthias, Rarey, Matthias, Jäger, Christian, Wieczorek, Vivien, Westerhoff, Lance M., Borbulevych, Oleg Y., Demuth, Hans-Ulrich, Buchholz, Mirko, Schmidt, Denis, Rickmeyer, Thomas, Krotzky, Timo, Kolb, Peter, Mittal, Sumit, Sánchez-García, Elsa, Nogueira, Mauro S., Oliveira, Tiago B., da Costa, Fernando B., Schmidt, Thomas J.
Argitaratua izan da J Cheminform (2016)