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Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism
Voltage-gated sodium channels are important targets for the development of pharmaceutical drugs, because mutations in different human sodium channel isoforms have causal relationships with a range of neurological and cardiovascular diseases. In this study, functional electrophysiological studies sho...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060673/ https://ncbi.nlm.nih.gov/pubmed/24850863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406855111 |
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