DNA shape, genetic codes, and evolution

Por Parker, Stephen C. J., Tullius, Thomas D.
Publicado em 2011

Detection of DNA structural motifs in functional genomic elements

Por Greenbaum, Jason A., Parker, Stephen C.J., Tullius, Thomas D.
Publicado em 2007

Motif signatures in stretch enhancers are enriched for disease-associated genetic variants

Por Quang, Daniel X, Erdos, Michael R, Parker, Stephen C J, Collins, Francis S
Publicado no Epigenetics Chromatin (2015)

Super Enhancers in Cancers, Complex Disease, and Developmental Disorders

Por Niederriter, Adrienne R., Varshney, Arushi, Parker, Stephen C. J., Martin, Donna M.
Publicado no Genes (Basel) (2015)

Local DNA Topography Correlates with Functional Noncoding Regions of the Human Genome

Por Parker, Stephen C.J., Hansen, Loren, Abaan, Hatice Ozel, Tullius, Thomas D., Margulies, Elliott H.
Publicado em 2009

A Bioinformatics Approach for Determining Sample Identity from Different Lanes of High-Throughput Sequencing Data

Por Goldfeder, Rachel L., Parker, Stephen C. J., Ajay, Subramanian S., Ozel Abaan, Hatice, Margulies, Elliott H.
Publicado em 2011

Accurate and comprehensive sequencing of personal genomes

Por Ajay, Subramanian S., Parker, Stephen C.J., Ozel Abaan, Hatice, Fuentes Fajardo, Karin V., Margulies, Elliott H.
Publicado em 2011

A Map of Minor Groove Shape and Electrostatic Potential from Hydroxyl Radical Cleavage Patterns of DNA

Por Bishop, Eric P., Rohs, Remo, Parker, Stephen C. J., West, Sean M., Liu, Peng, Mann, Richard S., Honig, Barry, Tullius, Thomas D.
Publicado em 2011

GBshape: a genome browser database for DNA shape annotations

Por Chiu, Tsu-Pei, Yang, Lin, Zhou, Tianyin, Main, Bradley J., Parker, Stephen C.J., Nuzhdin, Sergey V., Tullius, Thomas D., Rohs, Remo
Publicado no Nucleic Acids Res (2014)

Human NPY Promoter Variation rs16147:T>C as a Moderator of Prefrontal NPY Gene Expression and Negative Affect

Por Sommer, Wolfgang H., Lidström, Jessica, Sun, Hui, Passer, Derek, Eskay, Robert, Parker, Stephen C.J., Witt, Stephanie H., Zimmermann, Ulrich S., Nieratschker, Vanessa, Rietschel, Marcella, Margulies, Elliott H., Palkovits, Miklós, Laucht, Manfred, Heilig, Markus
Publicado em 2010

Family-Based Analysis of Candidate Genes for Polycystic Ovary Syndrome

Por Ewens, Kathryn G., Stewart, Douglas R., Ankener, Wendy, Urbanek, Margrit, McAllister, Jan M., Chen, Chen, Baig, K. Maravet, Parker, Stephen C. J., Margulies, Elliot H., Legro, Richard S., Dunaif, Andrea, Strauss, Jerome F., Spielman, Richard S.
Publicado em 2010

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

Por Stitzel, Michael L., Sethupathy, Praveen, Pearson, Daniel S., Chines, Peter S., Song, Lingyun, Erdos, Michael R., Welch, Ryan, Parker, Stephen C. J., Boyle, Alan P., Scott, Laura J., Margulies, Elliott H., Boehnke, Michael, Furey, Terrence S., Crawford, Gregory E., Collins, Francis S.
Publicado em 2010

Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection

Por Shibata, Yoichiro, Sheffield, Nathan C., Fedrigo, Olivier, Babbitt, Courtney C., Wortham, Matthew, Tewari, Alok K., London, Darin, Song, Lingyun, Lee, Bum-Kyu, Iyer, Vishwanath R., Parker, Stephen C. J., Margulies, Elliott H., Wray, Gregory A., Furey, Terrence S., Crawford, Gregory E.
Publicado em 2012

Somatic mutations in MAP3K5 attenuate its pro-apoptotic function in melanoma through increased binding to Thioredoxin

Por Prickett, Todd D., Zerlanko, Brad, Gartner, Jared J., Parker, Stephen C. J., Dutton-Regester, Ken, Lin, Jimmy C., Teer, Jamie K., Wei, Xiaomu, Jiang, Jiji, Chen, Guo, Davies, Michael A., Gershenwald, Jeffrey E., Robinson, William, Robinson, Steven, Hayward, Nicholas K., Rosenberg, Steven, A., Margulies, Elliott H., Samuels, Yardena
Publicado em 2013

Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes

Por Parker, Stephen C. J., Gartner, Jared, Cardenas-Navia, Isabel, Wei, Xiaomu, Ozel Abaan, Hatice, Ajay, Subramanian S., Hansen, Nancy F., Song, Lingyun, Bhanot, Umesh K., Killian, J. Keith, Gindin, Yevgeniy, Walker, Robert L., Meltzer, Paul S., Mullikin, James C., Furey, Terrence S., Crawford, Gregory E., Rosenberg, Steven A., Samuels, Yardena, Margulies, Elliott H.
Publicado em 2012

Genetic regulatory signatures underlying islet gene expression and type 2 diabetes

Por Varshney, Arushi, Scott, Laura J., Welch, Ryan P., Erdos, Michael R., Chines, Peter S., Narisu, Narisu, Albanus, Ricardo D’O., Orchard, Peter, Wolford, Brooke N., Kursawe, Romy, Vadlamudi, Swarooparani, Cannon, Maren E., Didion, John P., Hensley, John, Kirilusha, Anthony, Bonnycastle, Lori L., Taylor, D. Leland, Watanabe, Richard, Mohlke, Karen L., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J., Stitzel, Michael L.
Publicado no Proc Natl Acad Sci U S A (2017)

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

Por Gartner, Jared J., Parker, Stephen C. J., Prickett, Todd D., Dutton-Regester, Ken, Stitzel, Michael L., Lin, Jimmy C., Davis, Sean, Simhadri, Vijaya L., Jha, Sujata, Katagiri, Nobuko, Gotea, Valer, Teer, Jamie K., Wei, Xiaomu, Morken, Mario A., Bhanot, Umesh K., Chen, Guo, Elnitski, Laura L., Davies, Michael A., Gershenwald, Jeffrey E., Carter, Hannah, Karchin, Rachel, Robinson, William, Robinson, Steven, Rosenberg, Steven A., Collins, Francis S., Parmigiani, Giovanni, Komar, Anton A., Kimchi-Sarfaty, Chava, Hayward, Nicholas K., Margulies, Elliott H., Samuels, Yardena
Publicado em 2013

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

Por Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.
Publicado no Nat Commun (2016)

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

Por Parker, Stephen C. J., Stitzel, Michael L., Taylor, D. Leland, Orozco, Jose Miguel, Erdos, Michael R., Akiyama, Jennifer A., van Bueren, Kelly Lammerts, Chines, Peter S., Narisu, Narisu, Black, Brian L., Visel, Axel, Pennacchio, Len A., Collins, Francis S., Becker, Jesse, Benjamin, Betty, Blakesley, Robert, Bouffard, Gerry, Brooks, Shelise, Coleman, Holly, Dekhtyar, Mila, Gregory, Michael, Guan, Xiaobin, Gupta, Jyoti, Han, Joel, Hargrove, April, Ho, Shi-ling, Johnson, Taccara, Legaspi, Richelle, Lovett, Sean, Maduro, Quino, Masiello, Cathy, Maskeri, Baishali, McDowell, Jenny, Montemayor, Casandra, Mullikin, James, Park, Morgan, Riebow, Nancy, Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Mal, Thomas, James, Thomas, Pam, Vemulapalli, Meg, Young, Alice
Publicado em 2013

Comparative analysis of metazoan chromatin organization

Por Ho, Joshua W. K., Jung, Youngsook L., Liu, Tao, Alver, Burak H., Lee, Soohyun, Ikegami, Kohta, Sohn, Kyung-Ah, Minoda, Aki, Tolstorukov, Michael Y., Appert, Alex, Parker, Stephen C. J., Gu, Tingting, Kundaje, Anshul, Riddle, Nicole C., Bishop, Eric, Egelhofer, Thea A., Hu, Sheng’en Shawn, Alekseyenko, Artyom A., Rechtsteiner, Andreas, Asker, Dalal, Belsky, Jason A., Bowman, Sarah K., Chen, Q. Brent, Chen, Ron A-J, Day, Daniel S., Dong, Yan, Dose, Andrea C., Duan, Xikun, Epstein, Charles B., Ercan, Sevinc, Feingold, Elise A., Ferrari, Francesco, Garrigues, Jacob M., Gehlenborg, Nils, Good, Peter J., Haseley, Psalm, He, Daniel, Herrmann, Moritz, Hoffman, Michael M., Jeffers, Tess E., Kharchenko, Peter V., Kolasinska-Zwierz, Paulina, Kotwaliwale, Chitra V., Kumar, Nischay, Langley, Sasha A., Larschan, Erica N., Latorre, Isabel, Libbrecht, Maxwell W., Lin, Xueqiu, Park, Richard, Pazin, Michael J., Pham, Hoang N., Plachetka, Annette, Qin, Bo, Schwartz, Yuri B., Shoresh, Noam, Stempor, Przemyslaw, Vielle, Anne, Wang, Chengyang, Whittle, Christina M., Xue, Huiling, Kingston, Robert E., Kim, Ju Han, Bernstein, Bradley E., Dernburg, Abby F., Pirrotta, Vincenzo, Kuroda, Mitzi I., Noble, William S., Tullius, Thomas D., Kellis, Manolis, MacAlpine, David M., Strome, Susan, Elgin, Sarah C. R., Liu, Xiaole Shirley, Lieb, Jason D., Ahringer, Julie, Karpen, Gary H., Park, Peter J.
Publicado no Nature (2014)