Electronic health records: the next wave of complex disease genetics

著者: Wolford, Brooke N, Willer, Cristen J, Surakka, Ida
出版年 Hum Mol Genet (2018)

Aortic Progression and Reintervention in Patients with Pathogenic Variants Following a Thoracic Aortic Dissection

著者: Norton, Elizabeth L, Hornsby, Whitney E., Wu, Xiaoting, Wolford, Brooke N., Graham, Sarah E., Willer, Cristen J, Yang, Bo
出版年 J Thorac Cardiovasc Surg (2020)

Mitochondrial genome-wide association study of migraine – the HUNT Study

著者: Børte, Sigrid, Zwart, John-Anker, Skogholt, Anne Heidi, Gabrielsen, Maiken Elvestad, Thomas, Laurent F, Fritsche, Lars G, Surakka, Ida, Nielsen, Jonas B, Zhou, Wei, Wolford, Brooke N, Vigeland, Magnus D, Hagen, Knut, Kristoffersen, Espen Saxhaug, Nyholt, Dale R, Chasman, Daniel I, Brumpton, Ben M, Willer, Cristen J, Winsvold, Bendik S
出版年 Cephalalgia (2020)

A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression

著者: Kycia, Ina, Wolford, Brooke N., Huyghe, Jeroen R., Fuchsberger, Christian, Vadlamudi, Swarooparani, Kursawe, Romy, Welch, Ryan P., Albanus, Ricardo d’Oliveira, Uyar, Asli, Khetan, Shubham, Lawlor, Nathan, Bolisetty, Mohan, Mathur, Anubhuti, Kuusisto, Johanna, Laakso, Markku, Ucar, Duygu, Mohlke, Karen L., Boehnke, Michael, Collins, Francis S., Parker, Stephen C.J., Stitzel, Michael L.
出版年 Am J Hum Genet (2018)

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

著者: Zhou, Wei, Nielsen, Jonas B., Fritsche, Lars G., Dey, Rounak, Gabrielsen, Maiken E., Wolford, Brooke N., LeFaive, Jonathon, VandeHaar, Peter, Gagliano, Sarah A., Gifford, Aliya, Bastarache, Lisa A., Wei, Wei-Qi, Denny, Joshua C., Lin, Maoxuan, Hveem, Kristian, Kang, Hyun Min, Abecasis, Goncalo R., Willer, Cristen J., Lee, Seunggeun
出版年 Nat Genet (2018)

A Type 2 Diabetes–Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus

著者: Roman, Tamara S., Cannon, Maren E., Vadlamudi, Swarooparani, Buchkovich, Martin L., Wolford, Brooke N., Welch, Ryan P., Morken, Mario A., Kwon, Grace J., Varshney, Arushi, Kursawe, Romy, Wu, Ying, Jackson, Anne U., Erdos, Michael R., Kuusisto, Johanna, Laakso, Markku, Scott, Laura J., Boehnke, Michael, Collins, Francis S., Parker, Stephen C.J., Stitzel, Michael L., Mohlke, Karen L.
出版年 Diabetes (2017)

Genetic regulatory signatures underlying islet gene expression and type 2 diabetes

著者: Varshney, Arushi, Scott, Laura J., Welch, Ryan P., Erdos, Michael R., Chines, Peter S., Narisu, Narisu, Albanus, Ricardo D’O., Orchard, Peter, Wolford, Brooke N., Kursawe, Romy, Vadlamudi, Swarooparani, Cannon, Maren E., Didion, John P., Hensley, John, Kirilusha, Anthony, Bonnycastle, Lori L., Taylor, D. Leland, Watanabe, Richard, Mohlke, Karen L., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J., Stitzel, Michael L.
出版年 Proc Natl Acad Sci U S A (2017)

Clinical Implications of Identifying Pathogenic Variants in Individuals with Thoracic Aortic Dissection

著者: Wolford, Brooke N., Hornsby, Whitney E., Guo, Dongchuan, Zhou, Wei, Lin, Maoxuan, Farhat, Linda, McNamara, Jennifer, Driscoll, Anisa, Wu, Xiaoting, Schmidt, Ellen M., Norton, Elizabeth L., Mathis, Michael R., Ganesh, Santhi K., Douville, Nicholas J., Brummett, Chad M., Kitzman, Jacob, Chen, Y. Eugene, Kim, Karen, Deeb, G. Michael, Patel, Himanshu, Eagle, Kim A., Milewicz, Dianna M., Willer, Cristen J., Yang, Bo
出版年 Circ Genom Precis Med (2019)

Interactions between genetic variation and cellular environment in skeletal muscle gene expression

著者: Taylor, D. Leland, Knowles, David A., Scott, Laura J., Ramirez, Andrea H., Casale, Francesco Paolo, Wolford, Brooke N., Guan, Li, Varshney, Arushi, Albanus, Ricardo D’Oliveira, Parker, Stephen C. J., Narisu, Narisu, Chines, Peter S., Erdos, Michael R., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Stegle, Oliver, Boehnke, Michael, Birney, Ewan, Collins, Francis S.
出版年 PLoS One (2018)

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

著者: Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.
出版年 Nat Commun (2016)

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

著者: Nielsen, Jonas B., Fritsche, Lars G., Zhou, Wei, Teslovich, Tanya M., Holmen, Oddgeir L., Gustafsson, Stefan, Gabrielsen, Maiken E., Schmidt, Ellen M., Beaumont, Robin, Wolford, Brooke N., Lin, Maoxuan, Brummett, Chad M., Preuss, Michael H., Refsgaard, Lena, Bottinger, Erwin P., Graham, Sarah E., Surakka, Ida, Chu, Yunhan, Skogholt, Anne Heidi, Dalen, Håvard, Boyle, Alan P., Oral, Hakan, Herron, Todd J., Kitzman, Jacob, Jalife, José, Svendsen, Jesper H., Olesen, Morten S., Njølstad, Inger, Løchen, Maja-Lisa, Baras, Aris, Gottesman, Omri, Marcketta, Anthony, O’Dushlaine, Colm, Ritchie, Marylyn D., Wilsgaard, Tom, Loos, Ruth J.F., Frayling, Timothy M., Boehnke, Michael, Ingelsson, Erik, Carey, David J., Dewey, Frederick E., Kang, Hyun M., Abecasis, Gonçalo R., Hveem, Kristian, Willer, Cristen J.
出版年 Am J Hum Genet (2018)

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

著者: Nielsen, Jonas B., Thorolfsdottir, Rosa B., Fritsche, Lars G., Zhou, Wei, Skov, Morten W., Graham, Sarah E., Herron, Todd J., McCarthy, Shane, Schmidt, Ellen M., Sveinbjornsson, Gardar, Surakka, Ida, Mathis, Michael R., Yamazaki, Masatoshi, Crawford, Ryan D., Gabrielsen, Maiken E., Skogholt, Anne Heidi, Holmen, Oddgeir L., Lin, Maoxuan, Wolford, Brooke N., Dey, Rounak, Dalen, Håvard, Sulem, Patrick, Chung, Jonathan H., Backman, Joshua D., Arnar, David O., Thorsteinsdottir, Unnur, Baras, Aris, O’Dushlaine, Colm, Holst, Anders G., Wen, Xiaoquan, Hornsby, Whitney, Dewey, Frederick E., Boehnke, Michael, Kheterpal, Sachin, Mukherjee, Bhramar, Lee, Seunggeun, Kang, Hyun M., Holm, Hilma, Kitzman, Jacob, Shavit, Jordan A., Jalife, José, Brummett, Chad M., Teslovich, Tanya M., Carey, David J., Gudbjartsson, Daniel F., Stefansson, Kari, Abecasis, Gonçalo R., Hveem, Kristian, Willer, Cristen J.
出版年 Nat Genet (2018)

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

著者: Zhou, Wei, Brumpton, Ben, Kabil, Omer, Gudmundsson, Julius, Thorleifsson, Gudmar, Weinstock, Josh, Zawistowski, Matthew, Nielsen, Jonas B., Chaker, Layal, Medici, Marco, Teumer, Alexander, Naitza, Silvia, Sanna, Serena, Schultheiss, Ulla T., Cappola, Anne, Karjalainen, Juha, Kurki, Mitja, Oneka, Morgan, Taylor, Peter, Fritsche, Lars G., Graham, Sarah E., Wolford, Brooke N., Overton, William, Rasheed, Humaira, Haug, Eirin B., Gabrielsen, Maiken E., Skogholt, Anne Heidi, Surakka, Ida, Davey Smith, George, Pandit, Anita, Roychowdhury, Tanmoy, Hornsby, Whitney E., Jonasson, Jon G., Senter, Leigha, Liyanarachchi, Sandya, Ringel, Matthew D., Xu, Li, Kiemeney, Lambertus A., He, Huiling, Netea-Maier, Romana T., Mayordomo, Jose I., Plantinga, Theo S., Hrafnkelsson, Jon, Hjartarson, Hannes, Sturgis, Erich M., Palotie, Aarno, Daly, Mark, Citterio, Cintia E., Arvan, Peter, Brummett, Chad M., Boehnke, Michael, de la Chapelle, Albert, Stefansson, Kari, Hveem, Kristian, Willer, Cristen J., Åsvold, Bjørn Olav
出版年 Nat Commun (2020)

Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

著者: Klarin, Derek, Verma, Shefali Setia, Judy, Renae, Dikilitas, Ozan, Wolford, Brooke N., Paranjpe, Ishan, Levin, Michael G., Pan, Cuiping, Tcheandjieu, Catherine, Spin, Joshua M., Lynch, Julie, Assimes, Themistocles L., Åldstedt Nyrønning, Linn, Mattsson, Erney, Edwards, Todd L., Denny, Josh, Larson, Eric, Lee, Ming Ta Michael, Carrell, David, Zhang, Yanfei, Jarvik, Gail P., Gharavi, Ali G., Harley, John, Mentch, Frank, Pacheco, Jennifer A., Hakonarson, Hakon, Skogholt, Anne Heidi, Thomas, Laurent, Gabrielsen, Maiken Elvestad, Hveem, Kristian, Nielsen, Jonas Bille, Zhou, Wei, Fritsche, Lars, Huang, Jie, Natarajan, Pradeep, Sun, Yan V., DuVall, Scott L., Rader, Daniel J., Cho, Kelly, Chang, Kyong-Mi, Wilson, Peter W.F., O’Donnell, Christopher J., Kathiresan, Sekar, Scali, Salvatore T., Berceli, Scott A., Willer, Cristen, Jones, Gregory T., Bown, Matthew J., Nadkarni, Girish, Kullo, Iftikhar J., Ritchie, Marylyn, Damrauer, Scott M., Tsao, Philip S.
出版年 Circulation (2020)