Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

Abdominal aortic aneurysm (AAA) is an important cause of cardiovascular mortality; however, its genetic determinants remain incompletely defined. In total, 10 previously identified risk loci explain a small fraction of AAA heritability. METHODS: We performed a genome-wide association study in the Mi...

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Published in:Circulation
Main Authors: Klarin, Derek, Verma, Shefali Setia, Judy, Renae, Dikilitas, Ozan, Wolford, Brooke N., Paranjpe, Ishan, Levin, Michael G., Pan, Cuiping, Tcheandjieu, Catherine, Spin, Joshua M., Lynch, Julie, Assimes, Themistocles L., Åldstedt Nyrønning, Linn, Mattsson, Erney, Edwards, Todd L., Denny, Josh, Larson, Eric, Lee, Ming Ta Michael, Carrell, David, Zhang, Yanfei, Jarvik, Gail P., Gharavi, Ali G., Harley, John, Mentch, Frank, Pacheco, Jennifer A., Hakonarson, Hakon, Skogholt, Anne Heidi, Thomas, Laurent, Gabrielsen, Maiken Elvestad, Hveem, Kristian, Nielsen, Jonas Bille, Zhou, Wei, Fritsche, Lars, Huang, Jie, Natarajan, Pradeep, Sun, Yan V., DuVall, Scott L., Rader, Daniel J., Cho, Kelly, Chang, Kyong-Mi, Wilson, Peter W.F., O’Donnell, Christopher J., Kathiresan, Sekar, Scali, Salvatore T., Berceli, Scott A., Willer, Cristen, Jones, Gregory T., Bown, Matthew J., Nadkarni, Girish, Kullo, Iftikhar J., Ritchie, Marylyn, Damrauer, Scott M., Tsao, Philip S.
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2020
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Original Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7580856/
https://ncbi.nlm.nih.gov/pubmed/32981348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.047544
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