Meta-Analysis of Gene-Environment Interaction Exploiting Gene-Environment Independence Across Multiple Case-Control Studies

di Estes, Jason P., Rice, John D., Li, Shi, Stringham, Heather M., Boehnke, Michael, Mukherjee, Bhramar
Pubblicato in Stat Med (2017)

Subset-Based Analysis using Gene-Environment Interactions for Discovery of Genetic Associations across Multiple Studies or Phenotypes

di Yu, Youfei, Xia, Lu, Lee, Seunggeun, Zhou, Xiang, Stringham, Heather M, Boehnke, Michael, Mukherjee, Bhramar
Pubblicato in Hum Hered (2019)

The role of covariate heterogeneity in meta-analysis of gene-environment interactions with quantitative traits

di Li, Shi, Mukherjee, Bhramar, Taylor, Jeremy M.G., Rice, Kenneth M., XiaoquanWen, Rice, John D., Stringham, Heather M., Boehnke, Michael
Pubblicazione 2014

Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

di Kim, Daniel Seung, Jackson, Anne U., Li, Yatong K., Stringham, Heather M., Kuusisto, Johanna, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Burant, Charles F., Salomaa, Veikko, Boehnke, Michael, Laakso, Markku, Speliotes, Elizabeth K.
Pubblicato in J Lipid Res (2017)

Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose

di Li, Xia, Shu, Yu-Hsiang, Xiang, Anny H., Trigo, Enrique, Kuusisto, Johanna, Hartiala, Jaana, Swift, Amy J., Kawakubo, Miwa, Stringham, Heather M., Bonnycastle, Lori L., Lawrence, Jean M., Laakso, Markku, Allayee, Hooman, Buchanan, Thomas A., Watanabe, Richard M.
Pubblicazione 2009

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

di Davis, James P., Huyghe, Jeroen R., Locke, Adam E., Jackson, Anne U., Sim, Xueling, Stringham, Heather M., Teslovich, Tanya M., Welch, Ryan P., Fuchsberger, Christian, Narisu, Narisu, Chines, Peter S., Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Boehnke, Michael, Mohlke, Karen L.
Pubblicato in PLoS Genet (2017)

Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution

di Wu, Ying, Broadaway, K Alaine, Raulerson, Chelsea K, Scott, Laura J, Pan, Calvin, Ko, Arthur, He, Aiqing, Tilford, Charles, Fuchsberger, Christian, Locke, Adam E, Stringham, Heather M, Jackson, Anne U, Narisu, Narisu, Kuusisto, Johanna, Pajukanta, Päivi, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Lusis, Aldons J, Civelek, Mete, Mohlke, Karen L
Pubblicato in Hum Mol Genet (2019)

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

di Civelek, Mete, Wu, Ying, Pan, Calvin, Raulerson, Chelsea K., Ko, Arthur, He, Aiqing, Tilford, Charles, Saleem, Niyas K., Stančáková, Alena, Scott, Laura J., Fuchsberger, Christian, Stringham, Heather M., Jackson, Anne U., Narisu, Narisu, Chines, Peter S., Small, Kerrin S., Kuusisto, Johanna, Parks, Brian W., Pajukanta, Päivi, Kirchgessner, Todd, Collins, Francis S., Gargalovic, Peter S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L., Lusis, Aldons J.
Pubblicato in Am J Hum Genet (2017)

ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition

di El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Pubblicato in medRxiv (2020)

Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits

di Raulerson, Chelsea K., Ko, Arthur, Kidd, John C., Currin, Kevin W., Brotman, Sarah M., Cannon, Maren E., Wu, Ying, Spracklen, Cassandra N., Jackson, Anne U., Stringham, Heather M., Welch, Ryan P., Fuchsberger, Christian, Locke, Adam E., Narisu, Narisu, Lusis, Aldons J., Civelek, Mete, Furey, Terrence S., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Scott, Laura J., Lin, Dan-Yu, Love, Michael I., Laakso, Markku, Pajukanta, Päivi, Mohlke, Karen L.
Pubblicato in Am J Hum Genet (2019)

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

di Spracklen, Cassandra N., Iyengar, Apoorva K., Vadlamudi, Swarooparani, Raulerson, Chelsea K., Jackson, Anne U., Brotman, Sarah M., Wu, Ying, Cannon, Maren E., Davis, James P., Crain, Aaron T., Currin, Kevin W., Perrin, Hannah J., Narisu, Narisu, Stringham, Heather M., Fuchsberger, Christian, Locke, Adam E., Welch, Ryan P., Kuusisto, Johanna K., Pajukanta, Päivi, Scott, Laura J., Li, Yun, Collins, Francis S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L.
Pubblicato in PLoS Genet (2020)

Exome array analysis identifies novel loci and low-frequency variants for insulin processing and secretion

di Huyghe, Jeroen R, Jackson, Anne U, Fogarty, Marie P, Buchkovich, Martin L, Stančáková, Alena, Stringham, Heather M, Sim, Xueling, Yang, Lingyao, Fuchsberger, Christian, Cederberg, Henna, Chines, Peter S, Teslovich, Tanya M, Romm, Jane M, Ling, Hua, McMullen, Ivy, Ingersoll, Roxann, Pugh, Elizabeth W, Doheny, Kimberly F, Neale, Benjamin M, Daly, Mark J, Kuusisto, Johanna, Scott, Laura J, Kang, Hyun Min, Collins, Francis S, Abecasis, Gonçalo R, Watanabe, Richard M, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Pubblicazione 2012

Joint Analysis of Individual Participants’ Data from 17 Studies on the Association of the IL6 Variant -174G>C with Circulating Glucose Levels, Interleukin-6 Levels, and Body-Mass I...

di Huth, Cornelia, Illig, Thomas, Herder, Christian, Gieger, Christian, Grallert, Harald, Vollmert, Caren, Rathmann, Wolfgang, Hamid, Yasmin H., Pedersen, Oluf, Hansen, Torben, Thorand, Barbara, Meisinger, Christa, Döring, Angela, Klopp, Norman, Gohlke, Henning, Lieb, Wolfgang, Hengstenberg, Christian, Lyssenko, Valeriya, Groop, Leif, Ireland, Helen, Stephens, Jeffrey W., Asterholm, Ingrid Wernstedt, Jansson, John-Olov, Boeing, Heiner, Möhlig, Matthias, Stringham, Heather M., Boehnke, Michael, Tuomilehto, Jaakko, Fernandez-Real, Jose-Manuel, Lopez-Bermejo, Abel, Gallart, Luis, Vendrell, Joan, Humphries, Steve E., Kronenberg, Florian, Wichmann, H.-Erich, Heid, Iris M.
Pubblicazione 2009

Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

di Service, Susan K., Teslovich, Tanya M., Fuchsberger, Christian, Ramensky, Vasily, Yajnik, Pranav, Koboldt, Daniel C., Larson, David E., Zhang, Qunyuan, Lin, Ling, Welch, Ryan, Ding, Li, McLellan, Michael D., O'Laughlin, Michele, Fronick, Catrina, Fulton, Lucinda L., Magrini, Vincent, Swift, Amy, Elliott, Paul, Jarvelin, Marjo-Riitta, Kaakinen, Marika, McCarthy, Mark I., Peltonen, Leena, Pouta, Anneli, Bonnycastle, Lori L., Collins, Francis S., Narisu, Narisu, Stringham, Heather M., Tuomilehto, Jaakko, Ripatti, Samuli, Fulton, Robert S., Sabatti, Chiara, Wilson, Richard K., Boehnke, Michael, Freimer, Nelson B.
Pubblicazione 2014

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

di Jaiswal, Siddhartha, Fontanillas, Pierre, Flannick, Jason, Manning, Alisa, Grauman, Peter V., Mar, Brenton G., Lindsley, R. Coleman, Mermel, Craig H., Burtt, Noel, Chavez, Alejandro, Higgins, John M., Moltchanov, Vladislav, Kuo, Frank C., Kluk, Michael J., Henderson, Brian, Kinnunen, Leena, Koistinen, Heikki A., Ladenvall, Claes, Getz, Gad, Correa, Adolfo, Banahan, Benjamin F., Gabriel, Stacey, Kathiresan, Sekar, Stringham, Heather M., McCarthy, Mark I., Boehnke, Michael, Tuomilehto, Jaakko, Haiman, Christopher, Groop, Leif, Atzmon, Gil, Wilson, James G., Neuberg, Donna, Altshuler, David, Ebert, Benjamin L.
Pubblicato in N Engl J Med (2014)

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

di Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.
Pubblicato in Nat Commun (2016)

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study

di Teslovich, Tanya M, Kim, Daniel Seung, Yin, Xianyong, Stančáková, Alena, Jackson, Anne U, Wielscher, Matthias, Naj, Adam, Perry, John R B, Huyghe, Jeroen R, Stringham, Heather M, Davis, James P, Raulerson, Chelsea K, Welch, Ryan P, Fuchsberger, Christian, Locke, Adam E, Sim, Xueling, Chines, Peter S, Narisu, Narisu, Kangas, Antti J, Soininen, Pasi, Ala-Korpela, Mika, Gudnason, Vilmundur, Musani, Solomon K, Jarvelin, Marjo-Riitta, Schellenberg, Gerard D, Speliotes, Elizabeth K, Kuusisto, Johanna, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Pubblicato in Hum Mol Genet (2018)

Common variants in the GDF5-BFZB region are associated with variation in human height

di Sanna, Serena, Jackson, Anne U., Nagaraja, Ramaiah, Willer, Cristen J., Chen, Wei-Min, Bonnycastle, Lori L., Shen, Haiqing, Timpson, Nicholas, Lettre, Guillaume, Usala, Gianluca, Chines, Peter S., Stringham, Heather M., Dei, Mariano, Lai, Sandra, Albai, Giuseppe, Crisponi, Laura, Naitza, Silvia, Doheny, Kimberly F., Pugh, Elizabeth W., Ben-Shlomo, Yoav, Ebrahim, Shah, Lawlor, Debbie A., Bergman, Richard N., Watanabe, Richard M., Uda, Manuela, Tuomilehto, Jaakko, Coresh, Josef, Hirschhorn, Joel N., Shuldiner, Alan R., Schlessinger, David, Collins, Francis S., Smith, George Davey, Boerwinkle, Eric, Cao, Antonio, Boehnke, Michael, Abecasis, Gonçalo R., Mohlke, Karen L.
Pubblicazione 2008

A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants

di Scott, Laura J., Mohlke, Karen L., Bonnycastle, Lori L., Willer, Cristen J., Li, Yun, Duren, William L., Erdos, Michael R., Stringham, Heather M., Chines, Peter S., Jackson, Anne U., Prokunina-Olsson, Ludmila, Ding, Chia-Jen, Swift, Amy J., Narisu, Narisu, Hu, Tianle, Pruim, Randall, Xiao, Rui, Li, Xiao-Yi, Conneely, Karen N., Riebow, Nancy L., Sprau, Andrew G., Tong, Maurine, White, Peggy P., Hetrick, Kurt N., Barnhart, Michael W., Bark, Craig W., Goldstein, Janet L., Watkins, Lee, Xiang, Fang, Saramies, Jouko, Buchanan, Thomas A., Watanabe, Richard M., Valle, Timo T., Kinnunen, Leena, Abecasis, Gonçalo R., Pugh, Elizabeth W., Doheny, Kimberly F., Bergman, Richard N., Tuomilehto, Jaakko, Collins, Francis S., Boehnke, Michael
Pubblicazione 2007

Exome sequencing of Finnish isolates enhances rare-variant association power

di Locke, Adam E, Steinberg, Karyn Meltz, Chiang, Charleston WK, Service, Susan K, Havulinna, Aki S, Stell, Laurel, Pirinen, Matti, Abel, Haley J, Chiang, Colby C, Fulton, Robert S, Jackson, Anne U, Kang, Chul Joo, Kanchi, Krishna L, Koboldt, Daniel C, Larson, David E, Nelson, Joanne, Nicholas, Thomas J, Pietilä, Arto, Ramensky, Vasily, Ray, Debashree, Scott, Laura J, Stringham, Heather M, Vangipurapu, Jagadish, Welch, Ryan, Yajnik, Pranav, Yin, Xianyong, Eriksson, Johan G, Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Männikkö, Minna, Laivuori, Hannele, Dutcher, Susan K, Stitziel, Nathan O, Wilson, Richard K, Hall, Ira M, Sabatti, Chiara, Palotie, Aarno, Salomaa, Veikko, Laakso, Markku, Ripatti, Samuli, Boehnke, Michael, Freimer, Nelson B
Pubblicato in Nature (2019)