Meta-Analysis of Gene-Environment Interaction Exploiting Gene-Environment Independence Across Multiple Case-Control Studies

Autor Estes, Jason P., Rice, John D., Li, Shi, Stringham, Heather M., Boehnke, Michael, Mukherjee, Bhramar
Vydáno v Stat Med (2017)

Subset-Based Analysis using Gene-Environment Interactions for Discovery of Genetic Associations across Multiple Studies or Phenotypes

Autor Yu, Youfei, Xia, Lu, Lee, Seunggeun, Zhou, Xiang, Stringham, Heather M, Boehnke, Michael, Mukherjee, Bhramar
Vydáno v Hum Hered (2019)

The role of covariate heterogeneity in meta-analysis of gene-environment interactions with quantitative traits

Autor Li, Shi, Mukherjee, Bhramar, Taylor, Jeremy M.G., Rice, Kenneth M., XiaoquanWen, Rice, John D., Stringham, Heather M., Boehnke, Michael
Vydáno 2014

Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

Autor Kim, Daniel Seung, Jackson, Anne U., Li, Yatong K., Stringham, Heather M., Kuusisto, Johanna, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Burant, Charles F., Salomaa, Veikko, Boehnke, Michael, Laakso, Markku, Speliotes, Elizabeth K.
Vydáno v J Lipid Res (2017)

Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose

Autor Li, Xia, Shu, Yu-Hsiang, Xiang, Anny H., Trigo, Enrique, Kuusisto, Johanna, Hartiala, Jaana, Swift, Amy J., Kawakubo, Miwa, Stringham, Heather M., Bonnycastle, Lori L., Lawrence, Jean M., Laakso, Markku, Allayee, Hooman, Buchanan, Thomas A., Watanabe, Richard M.
Vydáno 2009

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

Autor Davis, James P., Huyghe, Jeroen R., Locke, Adam E., Jackson, Anne U., Sim, Xueling, Stringham, Heather M., Teslovich, Tanya M., Welch, Ryan P., Fuchsberger, Christian, Narisu, Narisu, Chines, Peter S., Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Boehnke, Michael, Mohlke, Karen L.
Vydáno v PLoS Genet (2017)

Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution

Autor Wu, Ying, Broadaway, K Alaine, Raulerson, Chelsea K, Scott, Laura J, Pan, Calvin, Ko, Arthur, He, Aiqing, Tilford, Charles, Fuchsberger, Christian, Locke, Adam E, Stringham, Heather M, Jackson, Anne U, Narisu, Narisu, Kuusisto, Johanna, Pajukanta, Päivi, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Lusis, Aldons J, Civelek, Mete, Mohlke, Karen L
Vydáno v Hum Mol Genet (2019)

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

Autor Civelek, Mete, Wu, Ying, Pan, Calvin, Raulerson, Chelsea K., Ko, Arthur, He, Aiqing, Tilford, Charles, Saleem, Niyas K., Stančáková, Alena, Scott, Laura J., Fuchsberger, Christian, Stringham, Heather M., Jackson, Anne U., Narisu, Narisu, Chines, Peter S., Small, Kerrin S., Kuusisto, Johanna, Parks, Brian W., Pajukanta, Päivi, Kirchgessner, Todd, Collins, Francis S., Gargalovic, Peter S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L., Lusis, Aldons J.
Vydáno v Am J Hum Genet (2017)

ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition

Autor El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Vydáno v medRxiv (2020)

Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits

Autor Raulerson, Chelsea K., Ko, Arthur, Kidd, John C., Currin, Kevin W., Brotman, Sarah M., Cannon, Maren E., Wu, Ying, Spracklen, Cassandra N., Jackson, Anne U., Stringham, Heather M., Welch, Ryan P., Fuchsberger, Christian, Locke, Adam E., Narisu, Narisu, Lusis, Aldons J., Civelek, Mete, Furey, Terrence S., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Scott, Laura J., Lin, Dan-Yu, Love, Michael I., Laakso, Markku, Pajukanta, Päivi, Mohlke, Karen L.
Vydáno v Am J Hum Genet (2019)

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

Autor Spracklen, Cassandra N., Iyengar, Apoorva K., Vadlamudi, Swarooparani, Raulerson, Chelsea K., Jackson, Anne U., Brotman, Sarah M., Wu, Ying, Cannon, Maren E., Davis, James P., Crain, Aaron T., Currin, Kevin W., Perrin, Hannah J., Narisu, Narisu, Stringham, Heather M., Fuchsberger, Christian, Locke, Adam E., Welch, Ryan P., Kuusisto, Johanna K., Pajukanta, Päivi, Scott, Laura J., Li, Yun, Collins, Francis S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L.
Vydáno v PLoS Genet (2020)

Exome array analysis identifies novel loci and low-frequency variants for insulin processing and secretion

Autor Huyghe, Jeroen R, Jackson, Anne U, Fogarty, Marie P, Buchkovich, Martin L, Stančáková, Alena, Stringham, Heather M, Sim, Xueling, Yang, Lingyao, Fuchsberger, Christian, Cederberg, Henna, Chines, Peter S, Teslovich, Tanya M, Romm, Jane M, Ling, Hua, McMullen, Ivy, Ingersoll, Roxann, Pugh, Elizabeth W, Doheny, Kimberly F, Neale, Benjamin M, Daly, Mark J, Kuusisto, Johanna, Scott, Laura J, Kang, Hyun Min, Collins, Francis S, Abecasis, Gonçalo R, Watanabe, Richard M, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Vydáno 2012

Joint Analysis of Individual Participants’ Data from 17 Studies on the Association of the IL6 Variant -174G>C with Circulating Glucose Levels, Interleukin-6 Levels, and Body-Mass I...

Autor Huth, Cornelia, Illig, Thomas, Herder, Christian, Gieger, Christian, Grallert, Harald, Vollmert, Caren, Rathmann, Wolfgang, Hamid, Yasmin H., Pedersen, Oluf, Hansen, Torben, Thorand, Barbara, Meisinger, Christa, Döring, Angela, Klopp, Norman, Gohlke, Henning, Lieb, Wolfgang, Hengstenberg, Christian, Lyssenko, Valeriya, Groop, Leif, Ireland, Helen, Stephens, Jeffrey W., Asterholm, Ingrid Wernstedt, Jansson, John-Olov, Boeing, Heiner, Möhlig, Matthias, Stringham, Heather M., Boehnke, Michael, Tuomilehto, Jaakko, Fernandez-Real, Jose-Manuel, Lopez-Bermejo, Abel, Gallart, Luis, Vendrell, Joan, Humphries, Steve E., Kronenberg, Florian, Wichmann, H.-Erich, Heid, Iris M.
Vydáno 2009

Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

Autor Service, Susan K., Teslovich, Tanya M., Fuchsberger, Christian, Ramensky, Vasily, Yajnik, Pranav, Koboldt, Daniel C., Larson, David E., Zhang, Qunyuan, Lin, Ling, Welch, Ryan, Ding, Li, McLellan, Michael D., O'Laughlin, Michele, Fronick, Catrina, Fulton, Lucinda L., Magrini, Vincent, Swift, Amy, Elliott, Paul, Jarvelin, Marjo-Riitta, Kaakinen, Marika, McCarthy, Mark I., Peltonen, Leena, Pouta, Anneli, Bonnycastle, Lori L., Collins, Francis S., Narisu, Narisu, Stringham, Heather M., Tuomilehto, Jaakko, Ripatti, Samuli, Fulton, Robert S., Sabatti, Chiara, Wilson, Richard K., Boehnke, Michael, Freimer, Nelson B.
Vydáno 2014

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Autor Jaiswal, Siddhartha, Fontanillas, Pierre, Flannick, Jason, Manning, Alisa, Grauman, Peter V., Mar, Brenton G., Lindsley, R. Coleman, Mermel, Craig H., Burtt, Noel, Chavez, Alejandro, Higgins, John M., Moltchanov, Vladislav, Kuo, Frank C., Kluk, Michael J., Henderson, Brian, Kinnunen, Leena, Koistinen, Heikki A., Ladenvall, Claes, Getz, Gad, Correa, Adolfo, Banahan, Benjamin F., Gabriel, Stacey, Kathiresan, Sekar, Stringham, Heather M., McCarthy, Mark I., Boehnke, Michael, Tuomilehto, Jaakko, Haiman, Christopher, Groop, Leif, Atzmon, Gil, Wilson, James G., Neuberg, Donna, Altshuler, David, Ebert, Benjamin L.
Vydáno v N Engl J Med (2014)

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

Autor Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.
Vydáno v Nat Commun (2016)

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study

Autor Teslovich, Tanya M, Kim, Daniel Seung, Yin, Xianyong, Stančáková, Alena, Jackson, Anne U, Wielscher, Matthias, Naj, Adam, Perry, John R B, Huyghe, Jeroen R, Stringham, Heather M, Davis, James P, Raulerson, Chelsea K, Welch, Ryan P, Fuchsberger, Christian, Locke, Adam E, Sim, Xueling, Chines, Peter S, Narisu, Narisu, Kangas, Antti J, Soininen, Pasi, Ala-Korpela, Mika, Gudnason, Vilmundur, Musani, Solomon K, Jarvelin, Marjo-Riitta, Schellenberg, Gerard D, Speliotes, Elizabeth K, Kuusisto, Johanna, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Vydáno v Hum Mol Genet (2018)

Common variants in the GDF5-BFZB region are associated with variation in human height

Autor Sanna, Serena, Jackson, Anne U., Nagaraja, Ramaiah, Willer, Cristen J., Chen, Wei-Min, Bonnycastle, Lori L., Shen, Haiqing, Timpson, Nicholas, Lettre, Guillaume, Usala, Gianluca, Chines, Peter S., Stringham, Heather M., Dei, Mariano, Lai, Sandra, Albai, Giuseppe, Crisponi, Laura, Naitza, Silvia, Doheny, Kimberly F., Pugh, Elizabeth W., Ben-Shlomo, Yoav, Ebrahim, Shah, Lawlor, Debbie A., Bergman, Richard N., Watanabe, Richard M., Uda, Manuela, Tuomilehto, Jaakko, Coresh, Josef, Hirschhorn, Joel N., Shuldiner, Alan R., Schlessinger, David, Collins, Francis S., Smith, George Davey, Boerwinkle, Eric, Cao, Antonio, Boehnke, Michael, Abecasis, Gonçalo R., Mohlke, Karen L.
Vydáno 2008

A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants

Autor Scott, Laura J., Mohlke, Karen L., Bonnycastle, Lori L., Willer, Cristen J., Li, Yun, Duren, William L., Erdos, Michael R., Stringham, Heather M., Chines, Peter S., Jackson, Anne U., Prokunina-Olsson, Ludmila, Ding, Chia-Jen, Swift, Amy J., Narisu, Narisu, Hu, Tianle, Pruim, Randall, Xiao, Rui, Li, Xiao-Yi, Conneely, Karen N., Riebow, Nancy L., Sprau, Andrew G., Tong, Maurine, White, Peggy P., Hetrick, Kurt N., Barnhart, Michael W., Bark, Craig W., Goldstein, Janet L., Watkins, Lee, Xiang, Fang, Saramies, Jouko, Buchanan, Thomas A., Watanabe, Richard M., Valle, Timo T., Kinnunen, Leena, Abecasis, Gonçalo R., Pugh, Elizabeth W., Doheny, Kimberly F., Bergman, Richard N., Tuomilehto, Jaakko, Collins, Francis S., Boehnke, Michael
Vydáno 2007

Exome sequencing of Finnish isolates enhances rare-variant association power

Autor Locke, Adam E, Steinberg, Karyn Meltz, Chiang, Charleston WK, Service, Susan K, Havulinna, Aki S, Stell, Laurel, Pirinen, Matti, Abel, Haley J, Chiang, Colby C, Fulton, Robert S, Jackson, Anne U, Kang, Chul Joo, Kanchi, Krishna L, Koboldt, Daniel C, Larson, David E, Nelson, Joanne, Nicholas, Thomas J, Pietilä, Arto, Ramensky, Vasily, Ray, Debashree, Scott, Laura J, Stringham, Heather M, Vangipurapu, Jagadish, Welch, Ryan, Yajnik, Pranav, Yin, Xianyong, Eriksson, Johan G, Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Männikkö, Minna, Laivuori, Hannele, Dutcher, Susan K, Stitziel, Nathan O, Wilson, Richard K, Hall, Ira M, Sabatti, Chiara, Palotie, Aarno, Salomaa, Veikko, Laakso, Markku, Ripatti, Samuli, Boehnke, Michael, Freimer, Nelson B
Vydáno v Nature (2019)