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Exome sequencing of Finnish isolates enhances rare-variant association power
Exome sequencing studies have generally been underpowered to identify deleterious alleles with a large effect on complex traits, as such alleles are mostly rare. Because the population of northern and eastern Finland has expanded dramatically and in isolation following a series of bottlenecks, it ha...
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| Publicat a: | Nature |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6697530/ https://ncbi.nlm.nih.gov/pubmed/31367044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1457-z |
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