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The role of covariate heterogeneity in meta-analysis of gene-environment interactions with quantitative traits

With challenges in data harmonization and covariate heterogeneity across various data sources, meta-analysis of gene-environment interaction studies can often involve subtle statistical issues. In this paper, we study the effect of environmental covariate heterogeneity (within and between cohorts) o...

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Detalhes bibliográficos
Main Authors: Li, Shi, Mukherjee, Bhramar, Taylor, Jeremy M.G., Rice, Kenneth M., XiaoquanWen, Rice, John D., Stringham, Heather M., Boehnke, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108593/
https://ncbi.nlm.nih.gov/pubmed/24801060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21810
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