Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes

Much emphasis has been placed on the identification, functional characterization, and therapeutic potential of somatic variants in tumor genomes. However, the majority of somatic variants lie outside coding regions and their role in cancer progression remains to be determined. In order to establish...

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Detalhes bibliográficos
Main Authors: Parker, Stephen C. J., Gartner, Jared, Cardenas-Navia, Isabel, Wei, Xiaomu, Ozel Abaan, Hatice, Ajay, Subramanian S., Hansen, Nancy F., Song, Lingyun, Bhanot, Umesh K., Killian, J. Keith, Gindin, Yevgeniy, Walker, Robert L., Meltzer, Paul S., Mullikin, James C., Furey, Terrence S., Crawford, Gregory E., Rosenberg, Steven A., Samuels, Yardena, Margulies, Elliott H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415438/
https://ncbi.nlm.nih.gov/pubmed/22912592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002871
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