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Accurate and comprehensive sequencing of personal genomes

As whole-genome sequencing becomes commoditized and we begin to sequence and analyze personal genomes for clinical and diagnostic purposes, it is necessary to understand what constitutes a complete sequencing experiment for determining genotypes and detecting single-nucleotide variants. Here, we sho...

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Main Authors: Ajay, Subramanian S., Parker, Stephen C.J., Ozel Abaan, Hatice, Fuentes Fajardo, Karin V., Margulies, Elliott H.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166834/
https://ncbi.nlm.nih.gov/pubmed/21771779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.123638.111
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