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Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma

BACKGROUND: Metastasis is characterized by spreading of neoplastic cells to an organ other than where they originated and is the predominant cause of death among cancer patients. This holds true for melanoma, whose incidence is increasing more rapidly than any other cancer and once disseminated has...

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Detalhes bibliográficos
Main Authors: Gartner, Jared J, Davis, Sean, Wei, Xiaomu, Lin, Jimmy C, Trivedi, Niraj S, Teer, Jamie K, Meltzer, Paul S, Rosenberg, Steven A, Samuels, Yardena
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500261/
https://ncbi.nlm.nih.gov/pubmed/23006843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-505
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