Exome sequencing identifies GRIN2A as frequently mutated in melanoma

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome sequencing of 14 matched normal and metastatic tumor DNAs. Using stringent criteria, we identified 68 genes th...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Wei, Xiaomu, Walia, Vijay, Lin, Jimmy C, Teer, Jamie K, Prickett, Todd D, Gartner, Jared, Davis, Sean, Stemke-Hale, Katherine, Davies, Michael A, Gershenwald, Jeffrey E, Robinson, William, Robinson, Steven, Rosenberg, Steven A, Samuels, Yardena
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161250/
https://ncbi.nlm.nih.gov/pubmed/21499247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.810
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares