Exome sequencing identifies GRIN2A as frequently mutated in melanoma

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome sequencing of 14 matched normal and metastatic tumor DNAs. Using stringent criteria, we identified 68 genes th...

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Detalhes bibliográficos
Main Authors: Wei, Xiaomu, Walia, Vijay, Lin, Jimmy C, Teer, Jamie K, Prickett, Todd D, Gartner, Jared, Davis, Sean, Stemke-Hale, Katherine, Davies, Michael A, Gershenwald, Jeffrey E, Robinson, William, Robinson, Steven, Rosenberg, Steven A, Samuels, Yardena
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161250/
https://ncbi.nlm.nih.gov/pubmed/21499247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.810
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