Exome sequencing identifies GRIN2A as frequently mutated in melanoma

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome sequencing of 14 matched normal and metastatic tumor DNAs. Using stringent criteria, we identified 68 genes th...

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Détails bibliographiques
Auteurs principaux: Wei, Xiaomu, Walia, Vijay, Lin, Jimmy C, Teer, Jamie K, Prickett, Todd D, Gartner, Jared, Davis, Sean, Stemke-Hale, Katherine, Davies, Michael A, Gershenwald, Jeffrey E, Robinson, William, Robinson, Steven, Rosenberg, Steven A, Samuels, Yardena
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161250/
https://ncbi.nlm.nih.gov/pubmed/21499247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.810
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