Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma

G protein-coupled receptors (GPCRs), the largest human gene family, are important regulators of signaling pathways. However, knowledge of their genetic alterations is limited. In this study, we used exon capture and massively parallel sequencing methods to analyze the mutational status of 734 GPCRs...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Prickett, Todd D, Wei, Xiaomu, Cardenas-Navia, Isabel, Teer, Jamie K, Lin, Jimmy C, Walia, Vijay, Gartner, Jared, Jiang, Jiji, Cherukuri, Praveen F, Molinolo, Alfredo, Davies, Michael A, Gershenwald, Jeffrey E, Stemke-Hale, Katherine, Rosenberg, Steven A, Margulies, Elliott H, Samuels, Yardena
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376644/
https://ncbi.nlm.nih.gov/pubmed/21946352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.950
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados