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Novel somatic mutations in heterotrimeric G proteins in melanoma
Heterotrimeric guanine nucleotide-binding proteins (G proteins) mediate signals between G-protein coupled receptors and their downstream pathways, and have been shown to be mutated in cancer. In particular, GNAQ was found to be frequently mutated in blue nevi of the skin and uveal melanoma, acting a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040832/ https://ncbi.nlm.nih.gov/pubmed/20424519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.1.11949 |
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