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Analysis of the Tyrosine Kinome in Melanoma Reveals Recurrent Mutations in ERBB4
Tyrosine phosphorylation is important in signaling pathways underlying tumorigenesis. A mutational analysis of the Protein Tyrosine Kinase (PTK) gene family in cutaneous metastatic melanoma identified 30 somatic mutations in the kinase domain of 19 PTKs. The whole of the coding region of these 19 PT...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897709/ https://ncbi.nlm.nih.gov/pubmed/19718025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.438 |
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