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Frequent Mutations in the MITF Pathway in Melanoma
MITF (Microphthalmia-associated transcription factor) is involved in melanocyte cell development, pigmentation and neoplasia. To determine whether MITF is somatically mutated in melanoma, we compared the sequence of MITF from primary and metastatic lesions to patient matched normal DNA. In the 50 me...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728363/ https://ncbi.nlm.nih.gov/pubmed/19422606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2009.00578.x |
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