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Frequent Mutations in the MITF Pathway in Melanoma

MITF (Microphthalmia-associated transcription factor) is involved in melanocyte cell development, pigmentation and neoplasia. To determine whether MITF is somatically mutated in melanoma, we compared the sequence of MITF from primary and metastatic lesions to patient matched normal DNA. In the 50 me...

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Detalhes bibliográficos
Main Authors: Cronin, Julia C., Wunderlich, John, Loftus, Stacie K., Prickett, Todd D., Wei, Xiaomu, Ridd, Katie, Vemula, Swapna, Burrell, Allison S., Agrawal, Neena S., Lin, Jimmy C., Banister, Carolyn E., Buckhaults, Phillip, Rosenberg, Steven A., Bastian, Boris C., Pavan, William J., Samuels, Yardena
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728363/
https://ncbi.nlm.nih.gov/pubmed/19422606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2009.00578.x
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