Frequent Mutations in the MITF Pathway in Melanoma

MITF (Microphthalmia-associated transcription factor) is involved in melanocyte cell development, pigmentation and neoplasia. To determine whether MITF is somatically mutated in melanoma, we compared the sequence of MITF from primary and metastatic lesions to patient matched normal DNA. In the 50 me...

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Autori principali: Cronin, Julia C., Wunderlich, John, Loftus, Stacie K., Prickett, Todd D., Wei, Xiaomu, Ridd, Katie, Vemula, Swapna, Burrell, Allison S., Agrawal, Neena S., Lin, Jimmy C., Banister, Carolyn E., Buckhaults, Phillip, Rosenberg, Steven A., Bastian, Boris C., Pavan, William J., Samuels, Yardena
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728363/
https://ncbi.nlm.nih.gov/pubmed/19422606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2009.00578.x
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