Effect of the rd1 mutation on motor performance in R6/2 and wild type mice

Por Menalled, Liliana, El-Khodor, Bassem F., Hornberger, Monica, Park, Larry, Howland, David, Brunner, Dani
Publicado em 2012

Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington’s Disease Patients

Por Naseri, Nima N., Bonica, Joseph, Xu, Hui, Park, Larry C., Arjomand, Jamshid, Chen, Zhengming, Gibson, Gary E.
Publicado no PLoS One (2016)

Pharmacokinetics of memantine in rats and mice

Por Beconi, Maria G., Howland, David, Park, Larry, Lyons, Kathryn, Giuliano, Joseph, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Pacifici, Robert
Publicado em 2012

Induction of Nitric Oxide Synthase and Microglial Responses Precede Selective Cell Death Induced by Chronic Impairment of Oxidative Metabolism

Por Calingasan, Noel Y., Park, Larry C. H., Calo, Leonard L., Trifiletti, Rosario R., Gandy, Samuel E., Gibson, Gary E.
Publicado em 1998

HD mouse models reveal clear deficits in learning to perform a simple instrumental response

Por Oakeshott, Stephen, Port, Russell G, Cummins-Sutphen, Jane, Watson-Johnson, Judy, Ramboz, Sylvie, Park, Larry, Howland, David, Brunner, Dani
Publicado em 2011

Abnormalities in the Tricarboxylic Acid Cycle in Huntington Disease and in a Huntington Disease Mouse Model

Por Naseri, Nima N., Xu, Hui, Bonica, Joseph, Vonsattel, Jean Paul G., Cortes, Etty P., Park, Larry C., Arjomand, Jamshid, Gibson, Gary E.
Publicado no J Neuropathol Exp Neurol (2015)

Cognitive Training at a Young Age Attenuates Deficits in the zQ175 Mouse Model of HD

Por Curtin, Paul C. P., Farrar, Andrew M., Oakeshott, Stephen, Sutphen, Jane, Berger, Jason, Mazzella, Matthew, Cox, Kimberly, He, Dansha, Alosio, William, Park, Larry C., Howland, David, Brunner, Daniela
Publicado no Front Behav Neurosci (2016)

Comprehensive Behavioral Testing in the R6/2 Mouse Model of Huntington's Disease Shows No Benefit from CoQ10 or Minocycline

Por Menalled, Liliana B., Patry, Monica, Ragland, Natalie, Lowden, Phillip A. S., Goodman, Jennifer, Minnich, Jennie, Zahasky, Benjamin, Park, Larry, Leeds, Janet, Howland, David, Signer, Ethan, Tobin, Allan J., Brunner, Daniela
Publicado em 2010

The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington’s Disease

Por Beaumont, Vahri, Park, Larry, Rassoulpour, Arash, Dijkman, Ulrike, Heikkinen, Taneli, Lehtimaki, Kimmo, Kontkanen, Outi, Al Nackkash, Rand, Bates, Gillian P., Gleyzes, Melanie, Steidl, Esther, Ramboz, Sylvie, Murphy, Carol, Beconi, Maria G., Dominguez, Celia, Munoz-Sanjuan, Ignacio
Publicado em 2014

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

Por Heikkinen, Taneli, Lehtimäki, Kimmo, Vartiainen, Nina, Puoliväli, Jukka, Hendricks, Susan J., Glaser, Jack R., Bradaia, Amyaouch, Wadel, Kristian, Touller, Chrystelle, Kontkanen, Outi, Yrjänheikki, Juha M., Buisson, Bruno, Howland, David, Beaumont, Vahri, Munoz-Sanjuan, Ignacio, Park, Larry C.
Publicado em 2012

Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment

Por Gafni, Juliette, Papanikolaou, Theodora, DeGiacomo, Francesco, Holcomb, Jennifer, Chen, Sylvia, Menalled, Liliana, Kudwa, Andrea, Fitzpatrick, Jon, Miller, Sam, Ramboz, Sylvie, Tuunanen, Pasi I., Lehtimäki, Kimmo K., Yang, X. William, Park, Larry, Kwak, Seung, Howland, David, Park, Hyunsun, Ellerby, Lisa M.
Publicado em 2012

Systematic behavioral evaluation of Huntington’s disease transgenic and knock-in mouse models

Por Menalled, Liliana, El-Khodor, Bassem F., Patry, Monica, Suarez-Farinas, Mayte, Orenstein, Samantha, Zahasky, Benjamin, Leahy, Christina, Wheeler, Vanessa, Yang, X. William, MacDonald, Marcy, Morton, Jennifer A., Bates, Gill, Leeds, Janet, Park, Larry, Howland, David, Signer, Ethan, Tobin, Allan, Brunner, Daniela
Publicado em 2009

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

Por Menalled, Liliana B., Kudwa, Andrea E., Miller, Sam, Fitzpatrick, Jon, Watson-Johnson, Judy, Keating, Nicole, Ruiz, Melinda, Mushlin, Richard, Alosio, William, McConnell, Kristi, Connor, David, Murphy, Carol, Oakeshott, Steve, Kwan, Mei, Beltran, Jose, Ghavami, Afshin, Brunner, Dani, Park, Larry C., Ramboz, Sylvie, Howland, David
Publicado em 2012

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

Por Mielcarek, Michal, Landles, Christian, Weiss, Andreas, Bradaia, Amyaouch, Seredenina, Tamara, Inuabasi, Linda, Osborne, Georgina F., Wadel, Kristian, Touller, Chrystelle, Butler, Rachel, Robertson, Janette, Franklin, Sophie A., Smith, Donna L., Park, Larry, Marks, Paul A., Wanker, Erich E., Olson, Eric N., Luthi-Carter, Ruth, van der Putten, Herman, Beaumont, Vahri, Bates, Gillian P.
Publicado em 2013

Genetic Deletion of Transglutaminase 2 Does Not Rescue the Phenotypic Deficits Observed in R6/2 and zQ175 Mouse Models of Huntington's Disease

Por Menalled, Liliana B., Kudwa, Andrea E., Oakeshott, Steve, Farrar, Andrew, Paterson, Neil, Filippov, Igor, Miller, Sam, Kwan, Mei, Olsen, Michael, Beltran, Jose, Torello, Justin, Fitzpatrick, Jon, Mushlin, Richard, Cox, Kimberly, McConnell, Kristi, Mazzella, Matthew, He, Dansha, Osborne, Georgina F., Al-Nackkash, Rand, Bates, Gill P., Tuunanen, Pasi, Lehtimaki, Kimmo, Brunner, Dani, Ghavami, Afshin, Ramboz, Sylvie, Park, Larry, Macdonald, Douglas, Munoz-Sanjuan, Ignacio, Howland, David
Publicado em 2014