Progressive Volume Loss and White Matter Degeneration in Cstb-Deficient Mice: A Diffusion Tensor and Longitudinal Volumetry MRI Study

Por Manninen, Otto, Laitinen, Teemu, Lehtimäki, Kimmo K., Tegelberg, Saara, Lehesjoki, Anna-Elina, Gröhn, Olli, Kopra, Outi
Publicado em 2014

The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain

Por Datson, Nicole A., González-Barriga, Anchel, Kourkouta, Eleni, Weij, Rudie, van de Giessen, Jeroen, Mulders, Susan, Kontkanen, Outi, Heikkinen, Taneli, Lehtimäki, Kimmo, van Deutekom, Judith C. T.
Publicado no PLoS One (2017)

mNos2 Deletion and Human NOS2 Replacement in Alzheimer Disease Models

Por Colton, Carol A., Wilson, Joan G., Everhart, Angela, Wilcock, Donna M., Puoliväli, Jukka, Heikkinen, Taneli, Oksman, Juho, Jääskeläinen, Olli, Lehtimäki, Kimmo, Laitinen, Teemu, Vartiainen, Nina, Vitek, Michael P.
Publicado em 2014

Hip region muscular dystrophy and emergence of motor deficits in dysferlin‐deficient Bla/J mice

Por Nagy, Nadia, Nonneman, Randal J., Llanga, Telmo, Dial, Catherine F., Riddick, Natallia V., Hampton, Tom, Moy, Sheryl S., Lehtimäki, Kimmo K., Ahtoniemi, Toni, Puoliväli, Jukka, Windish, Hillarie, Albrecht, Douglas, Richard, Isabelle, Hirsch, Matthew L.
Publicado no Physiol Rep (2017)

Effect of Ibuprofen on Skeletal Muscle of Dysferlin-Null Mice

Por Collier, Alyssa F., Gumerson, Jessica, Lehtimäki, Kimmo, Puoliväli, Jukka, Jones, Jace W., Kane, Maureen A., Manne, Sankeerth, O’Neill, Andrea, Windish, Hillarie P., Ahtoniemi, Toni, Williams, Bradley A., Albrecht, Douglas E., Bloch, Robert J.
Publicado no J Pharmacol Exp Ther (2018)

The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington’s Disease

Por Beaumont, Vahri, Park, Larry, Rassoulpour, Arash, Dijkman, Ulrike, Heikkinen, Taneli, Lehtimaki, Kimmo, Kontkanen, Outi, Al Nackkash, Rand, Bates, Gillian P., Gleyzes, Melanie, Steidl, Esther, Ramboz, Sylvie, Murphy, Carol, Beconi, Maria G., Dominguez, Celia, Munoz-Sanjuan, Ignacio
Publicado em 2014

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

Por Heikkinen, Taneli, Lehtimäki, Kimmo, Vartiainen, Nina, Puoliväli, Jukka, Hendricks, Susan J., Glaser, Jack R., Bradaia, Amyaouch, Wadel, Kristian, Touller, Chrystelle, Kontkanen, Outi, Yrjänheikki, Juha M., Buisson, Bruno, Howland, David, Beaumont, Vahri, Munoz-Sanjuan, Ignacio, Park, Larry C.
Publicado em 2012

Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment

Por Gafni, Juliette, Papanikolaou, Theodora, DeGiacomo, Francesco, Holcomb, Jennifer, Chen, Sylvia, Menalled, Liliana, Kudwa, Andrea, Fitzpatrick, Jon, Miller, Sam, Ramboz, Sylvie, Tuunanen, Pasi I., Lehtimäki, Kimmo K., Yang, X. William, Park, Larry, Kwak, Seung, Howland, David, Park, Hyunsun, Ellerby, Lisa M.
Publicado em 2012

Genetic Deletion of Transglutaminase 2 Does Not Rescue the Phenotypic Deficits Observed in R6/2 and zQ175 Mouse Models of Huntington's Disease

Por Menalled, Liliana B., Kudwa, Andrea E., Oakeshott, Steve, Farrar, Andrew, Paterson, Neil, Filippov, Igor, Miller, Sam, Kwan, Mei, Olsen, Michael, Beltran, Jose, Torello, Justin, Fitzpatrick, Jon, Mushlin, Richard, Cox, Kimberly, McConnell, Kristi, Mazzella, Matthew, He, Dansha, Osborne, Georgina F., Al-Nackkash, Rand, Bates, Gill P., Tuunanen, Pasi, Lehtimaki, Kimmo, Brunner, Dani, Ghavami, Afshin, Ramboz, Sylvie, Park, Larry, Macdonald, Douglas, Munoz-Sanjuan, Ignacio, Howland, David
Publicado em 2014

Inaugural Charles River World Congress on Animal Models in Drug Discovery and Development

Por Berzofsky, Jay A., Koch, Lauren Gerard, Britton, Steven L., Chen, Shaochen, Zhu, Wei, Ma, Xuanyi, Comuzzie, Anthony G., Devy-Dimanche, Laetitia, Feaver, Ryan, Grimm, Jan, Hock, Christoph, Nitsch, Roger M., Hoying, James B., Lusis, Aldons J., Marincola, Francesco, Samayoa, Josue, Turan, Tolga, Pearce, David A., Nurmi, Antti, Huhtala, Tuulia, Shatillo, Artem, Puoliväli, Jukka, Heikkinen, Taneli, Bragge, Timo, Lehtimäki, Kimmo, Sanyal, Arun J., Strange, Kevin, Taylor, D. Lansing, Miedel, Mark, Jia, Shanhang, Soto-Guterriez, Alex, Stern, Andrew, Gough, Albert
Publicado no J Transl Med (2017)