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HD mouse models reveal clear deficits in learning to perform a simple instrumental response
Mouse models of Huntington’s disease (HD) were trained to acquire one of two simple instrumental responses (a lever press or a nosepoke) to obtain food reinforcement. Animals from several HD strains revealed apparently progressive deficits in this task, being significantly less able than littermate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327146/ https://ncbi.nlm.nih.gov/pubmed/22512000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1282 |
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