Cognitive Training at a Young Age Attenuates Deficits in the zQ175 Mouse Model of HD

Huntington's Disease (HD) is a progressive neurodegenerative disorder that causes motor, cognitive, and psychiatric symptoms. In these experiments, we tested if operant training at an early age affected adult cognitive deficits in the zQ175 KI Het (zQ175) mouse model of HD. In Experiment 1 we t...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Curtin, Paul C. P., Farrar, Andrew M., Oakeshott, Stephen, Sutphen, Jane, Berger, Jason, Mazzella, Matthew, Cox, Kimberly, He, Dansha, Alosio, William, Park, Larry C., Howland, David, Brunner, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707270/
https://ncbi.nlm.nih.gov/pubmed/26793080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2015.00361
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