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Abnormalities in the Tricarboxylic Acid Cycle in Huntington Disease and in a Huntington Disease Mouse Model

Glucose metabolism is reduced in the brains of patients with Huntington disease (HD). The mechanisms underlying this deficit, its link to the pathology of the disease and the vulnerability of the striatum in HD remain unknown. Abnormalities in some of the key mitochondrial enzymes involved in glucos...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Naseri, Nima N., Xu, Hui, Bonica, Joseph, Vonsattel, Jean Paul G., Cortes, Etty P., Park, Larry C., Arjomand, Jamshid, Gibson, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435838/
https://ncbi.nlm.nih.gov/pubmed/25978848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000197
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