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Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria.
Methylmalonic acidemia (MMA) is a propionate pathway disorder caused by dysfunction of the mitochondrial enzyme methylmalonyl-CoA mutase (MMUT). MMUT catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA, an anaplerotic reaction which feeds into the tricarboxylic acid (TCA) cycle. As part of...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Genet Metab |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6903684/ https://ncbi.nlm.nih.gov/pubmed/31648943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2019.10.007 |
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