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Pharmacokinetics of memantine in rats and mice

To evaluate the potential of memantine as a therapeutic agent for Huntington’s disease (HD) we have undertaken a series of in vitro, ex vivo and whole animal studies to characterize its pharmacokinetics (PK) and pharmacodynamics (PD) in rats and mice. Results from these studies will enable determina...

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Detalhes bibliográficos
Main Authors: Beconi, Maria G., Howland, David, Park, Larry, Lyons, Kathryn, Giuliano, Joseph, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Pacifici, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269340/
https://ncbi.nlm.nih.gov/pubmed/22307216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1291
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