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Effect of the rd1 mutation on motor performance in R6/2 and wild type mice
Homozygosis for the rd1 mutation in the Pbe6b gene results in the loss of the rod beta-subunit of the cyclic GMP phosphodiesterase and, eventually, of all rod and cone photoreceptors. The R6/2 mouse line is a widely used model of Huntington’s disease (HD). The original line was made available on a m...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278853/ https://ncbi.nlm.nih.gov/pubmed/22367489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1303 |
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