Comprehensive Behavioral Testing in the R6/2 Mouse Model of Huntington's Disease Shows No Benefit from CoQ10 or Minocycline

Previous studies of the effects of coenzyme Q10 and minocycline on mouse models of Huntington's disease have produced conflicting results regarding their efficacy in behavioral tests. Using our recently published best practices for husbandry and testing for mouse models of Huntington's dis...

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Hlavní autoři: Menalled, Liliana B., Patry, Monica, Ragland, Natalie, Lowden, Phillip A. S., Goodman, Jennifer, Minnich, Jennie, Zahasky, Benjamin, Park, Larry, Leeds, Janet, Howland, David, Signer, Ethan, Tobin, Allan J., Brunner, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842438/
https://ncbi.nlm.nih.gov/pubmed/20339553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009793
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