Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases

per Rodgers, Samuel J., Ferguson, Daniel T., Mitchell, Christina A., Ooms, Lisa M.
Publicat a Biosci Rep (2017)

PTEN and Other PtdIns(3,4,5)P(3) Lipid Phosphatases in Breast Cancer

per Csolle, Mariah P., Ooms, Lisa M., Papa, Antonella, Mitchell, Christina A.
Publicat a Int J Mol Sci (2020)

A Mutation in Synaptojanin 2 Causes Progressive Hearing Loss in the ENU-Mutagenised Mouse Strain Mozart

per Manji, Shehnaaz S. M., Williams, Louise H., Miller, Kerry A., Ooms, Lisa M., Bahlo, Melanie, Mitchell, Christina A., Dahl, Hans-Henrik M.
Publicat 2011

The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Br...

per Lucato, Christina M., Halls, Michelle L., Ooms, Lisa M., Liu, Heng-Jia, Mitchell, Christina A., Whisstock, James C., Ellisdon, Andrew M.
Publicat a J Biol Chem (2015)

The Shc-binding site of the β(c) subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

per Ramshaw, Hayley S., Guthridge, Mark A., Stomski, Frank C., Barry, Emma F., Ooms, Lisa, Mitchell, Christina A., Begley, C. Glenn, Lopez, Angel F.
Publicat 2007

The Yeast Inositol Polyphosphate 5-Phosphatases Inp52p and Inp53p Translocate to Actin Patches following Hyperosmotic Stress: Mechanism for Regulating Phosphatidylinositol 4,5-Bis...

per Ooms, Lisa M., McColl, Brad K., Wiradjaja, Fenny, Wijayaratnam, A. P. W., Gleeson, Paul, Gething, Mary Jane, Sambrook, Joe, Mitchell, Christina A.
Publicat 2000

Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)·Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation

per Astle, Megan V., Ooms, Lisa M., Cole, Adam R., Binge, Lauren C., Dyson, Jennifer M., Layton, Meredith J., Petratos, Steven, Sutherland, Calum, Mitchell, Christina A.
Publicat 2011

The Inositol Polyphosphate 5-Phosphatase, PIPP, Is a Novel Regulator of Phosphoinositide 3-Kinase-dependent Neurite Elongation

per Ooms, Lisa M., Fedele, Clare G., Astle, Megan V., Ivetac, Ivan, Cheung, Vanessa, Pearson, Richard B., Layton, Meredith J., Forrai, Ariel, Nandurkar, Harshal H., Mitchell, Christina A.
Publicat 2006

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

per Dyson, Jennifer M., O'Malley, Cindy J., Becanovic, Jelena, Munday, Adam D., Berndt, Michael C., Coghill, Imogen D., Nandurkar, Harshal H., Ooms, Lisa M., Mitchell, Christina A.
Publicat 2001

Silencer of Death Domains (SODD) Inhibits Skeletal Muscle and Kidney Enriched Inositol 5-Phosphatase (SKIP) and Regulates Phosphoinositide 3-Kinase (PI3K)/Akt Signaling to the Acti...

per Rahman, Parvin, Huysmans, Richard D., Wiradjaja, Fenny, Gurung, Rajendra, Ooms, Lisa M., Sheffield, David A., Dyson, Jennifer M., Layton, Meredith J., Sriratana, Absorn, Takada, Hidetoshi, Tiganis, Tony, Mitchell, Christina A.
Publicat 2011

PtdIns(3,4,5)P(3)-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation...

per Liu, Heng-Jia, Ooms, Lisa M., Srijakotre, Nuthasuda, Man, Joey, Vieusseux, Jessica, Waters, JoAnne E., Feng, Yue, Bailey, Charles G., Rasko, John E. J., Price, John T., Mitchell, Christina A.
Publicat a J Biol Chem (2016)

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

per Wu, Guojie, Mazzitelli, Blake A., Quek, Adam J., Veldman, Matthew J., Conroy, Paul J., Caradoc-Davies, Tom T., Ooms, Lisa M., Tuck, Kellie L., Schoenecker, Jonathan G., Whisstock, James C., Law, Ruby H. P.
Publicat a Blood Adv (2019)

PtdIns(3,4,5)P(3)-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis

per Srijakotre, Nuthasuda, Liu, Heng-Jia, Nobis, Max, Man, Joey, Yip, Hon Yan Kelvin, Papa, Antonella, Abud, Helen E., Anderson, Kurt I., Welch, Heidi C. E., Tiganis, Tony, Timpson, Paul, McLean, Catriona A., Ooms, Lisa M., Mitchell, Christina A.
Publicat a Proc Natl Acad Sci U S A (2020)

Reactive oxygen species enhance insulin sensitivity

per Loh, Kim, Deng, Haiyang, Fukushima, Atsushi, Cai, Xiaochu, Boivin, Benoit, Galic, Sandra, Bruce, Clinton, Shields, Benjamin J., Skiba, Beata, Ooms, Lisa M., Stepto, Nigel, Wu, Ben, Mitchell, Christina A., Tonks, Nicholas K., Watt, Matthew J., Febbraio, Mark A., Crack, Peter J., Andrikopoulos, Sofianos, Tiganis, Tony
Publicat 2009

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

per Fedele, Clare G., Ooms, Lisa M., Ho, Miriel, Vieusseux, Jessica, O'Toole, Sandra A., Millar, Ewan K., Lopez-Knowles, Elena, Sriratana, Absorn, Gurung, Rajendra, Baglietto, Laura, Giles, Graham G., Bailey, Charles G., Rasko, John E. J., Shields, Benjamin J., Price, John T., Majerus, Philip W., Sutherland, Robert L., Tiganis, Tony, McLean, Catriona A., Mitchell, Christina A.
Publicat 2010

INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer

per Rodgers, Samuel J., Ooms, Lisa M., Oorschot, Viola M. J., Schittenhelm, Ralf B., Nguyen, Elizabeth V., Hamila, Sabryn A., Rynkiewicz, Natalie, Gurung, Rajendra, Eramo, Matthew J., Sriratana, Absorn, Fedele, Clare G., Caramia, Franco, Loi, Sherene, Kerr, Genevieve, Abud, Helen E., Ramm, Georg, Papa, Antonella, Ellisdon, Andrew M., Daly, Roger J., McLean, Catriona A., Mitchell, Christina A.
Publicat a Nat Commun (2021)