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Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)·Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation

Neuron polarization is essential for the formation of one axon and multiple dendrites, establishing the neuronal circuitry. Phosphoinositide 3-kinase (PI3K) signaling promotes axon selection and elongation. Here we report in hippocampal neurons siRNA knockdown of the proline-rich inositol polyphosph...

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Detalhes bibliográficos
Principais autores: Astle, Megan V., Ooms, Lisa M., Cole, Adam R., Binge, Lauren C., Dyson, Jennifer M., Layton, Meredith J., Petratos, Steven, Sutherland, Calum, Mitchell, Christina A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123105/
https://ncbi.nlm.nih.gov/pubmed/21550974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.214247
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