Science amongst the vines. Meeting on Signalling Systems

Por Pitson, Stuart M, Goodall, Gregory J, Guthridge, Mark A
Publicado em 2008

Fibroblast Growth Factor Receptor 2 Phosphorylation on Serine 779 Couples to 14-3-3 and Regulates Cell Survival and Proliferation

Por Lonic, Ana, Barry, Emma F., Quach, Cindy, Kobe, Bostjan, Saunders, Neil, Guthridge, Mark A.
Publicado em 2008

Oncogenic Mutations of p110α Isoform of PI 3-Kinase Upregulate Its Protein Kinase Activity

Por Buchanan, Christina M., Dickson, James M. J., Lee, Woo-Jeong, Guthridge, Mark A., Kendall, Jackie D., Shepherd, Peter R.
Publicado em 2013

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

Por Hercus, Timothy R., Thomas, Daniel, Guthridge, Mark A., Ekert, Paul G., King-Scott, Jack, Parker, Michael W., Lopez, Angel F.
Publicado em 2009

Phosphorylation of Serine 779 in Fibroblast Growth Factor Receptor 1 and 2 by Protein Kinase Cϵ Regulates Ras/Mitogen-activated Protein Kinase Signaling and Neuronal Differentiatio...

Por Lonic, Ana, Powell, Jason A., Kong, Yang, Thomas, Daniel, Holien, Jessica K., Truong, Nhan, Parker, Michael W., Guthridge, Mark A.
Publicado em 2013

The Shc-binding site of the β(c) subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

Por Ramshaw, Hayley S., Guthridge, Mark A., Stomski, Frank C., Barry, Emma F., Ooms, Lisa, Mitchell, Christina A., Begley, C. Glenn, Lopez, Angel F.
Publicado em 2007

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

Por Guthridge, Mark A, Powell, Jason A, Barry, Emma F, Stomski, Frank C, McClure, Barbara J, Ramshaw, Hayley, Felquer, Fernando A, Dottore, Mara, Thomas, Daniel T, To, Bik, Begley, C Glenn, Lopez, Angel F
Publicado em 2006

14-3-3:Shc Scaffolds Integrate Phosphoserine and Phosphotyrosine Signaling to Regulate Phosphatidylinositol 3-Kinase Activation and Cell Survival

Por Barry, Emma F., Felquer, Fernando A., Powell, Jason A., Biggs, Lisa, Stomski, Frank C., Urbani, Andrea, Ramshaw, Hayley, Hoffmann, Peter, Wilce, Matthew C., Grimbaldeston, Michele A., Lopez, Angel F., Guthridge, Mark A.
Publicado em 2009

14-3-3ζ coordinates adipogenesis of visceral fat

Por Lim, Gareth E., Albrecht, Tobias, Piske, Micah, Sarai, Karnjit, Lee, Jason T. C, Ramshaw, Hayley S., Sinha, Sunita, Guthridge, Mark A., Acker-Palmer, Amparo, Lopez, Angel F., Clee, Susanne M., Nislow, Corey, Johnson, James D.
Publicado no Nat Commun (2015)

Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT(+) cancers

Por Roberts, Kathryn G., Smith, Amanda M., McDougall, Fiona, Carpenter, Helen, Horan, Martin, Neviani, Paolo, Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Perrotti, Danilo, Sim, Alistair T.R., Ashman, Leonie K., Verrills, Nicole M.
Publicado em 2010

Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival

Por Thomas, Daniel, Powell, Jason A., Green, Benjamin D., Barry, Emma F., Ma, Yuefang, Woodcock, Joanna, Fitter, Stephen, Zannettino, Andrew C. W., Pitson, Stuart M., Hughes, Timothy P., Lopez, Angel F., Shepherd, Peter R., Wei, Andrew H., Ekert, Paul G., Guthridge, Mark A.
Publicado em 2013

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

Por Smith, Amanda M., Dun, Matthew D., Lee, Erwin M., Harrison, Celeste, Kahl, Richard, Flanagan, Hayley, Panicker, Nikita, Mashkani, Baratali, Don, Anthony S., Morris, Jonathan, Toop, Hamish, Lock, Richard B., Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Moore, Andrew, Ashman, Leonie K., Skelding, Kathryn A., Enjeti, Anoop, Verrills, Nicole M.
Publicado no Oncotarget (2016)

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Por Hein, Nadine, Cameron, Donald P., Hannan, Katherine M., Nguyen, Nhu-Y N., Fong, Chun Yew, Sornkom, Jirawas, Wall, Meaghan, Pavy, Megan, Cullinane, Carleen, Diesch, Jeannine, Devlin, Jennifer R., George, Amee J., Sanij, Elaine, Quin, Jaclyn, Poortinga, Gretchen, Verbrugge, Inge, Baker, Adele, Drygin, Denis, Harrison, Simon J., Rozario, James D., Powell, Jason A., Pitson, Stuart M., Zuber, Johannes, Johnstone, Ricky W., Dawson, Mark A., Guthridge, Mark A., Wei, Andrew, McArthur, Grant A., Pearson, Richard B., Hannan, Ross D.
Publicado no Blood (2017)