14-3-3:Shc Scaffolds Integrate Phosphoserine and Phosphotyrosine Signaling to Regulate Phosphatidylinositol 3-Kinase Activation and Cell Survival

Integrated cascades of protein tyrosine and serine/threonine phosphorylation play essential roles in transducing signals in response to growth factors and cytokines. How adaptor or scaffold proteins assemble signaling complexes through both phosphotyrosine and phosphoserine/threonine residues to reg...

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Detalhes bibliográficos
Main Authors: Barry, Emma F., Felquer, Fernando A., Powell, Jason A., Biggs, Lisa, Stomski, Frank C., Urbani, Andrea, Ramshaw, Hayley, Hoffmann, Peter, Wilce, Matthew C., Grimbaldeston, Michele A., Lopez, Angel F., Guthridge, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673277/
https://ncbi.nlm.nih.gov/pubmed/19218246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807637200
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