New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

Most, if not all, cytokines activate phosphatidylinositol 3-kinase (PI-3K). Although many cytokine receptors have direct binding sites for the p85 subunit of PI-3K, others, such as the interleukin-3 (IL-3) receptor beta common chain (βc) and the IL-2 receptor beta chain (IL-2Rβ), lack such sites, le...

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Hlavní autoři: Gu, Haihua, Maeda, Hiroyuki, Moon, James J., Lord, James D., Yoakim, Monique, Nelson, Brad H., Neel, Benjamin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86258/
https://ncbi.nlm.nih.gov/pubmed/10982827
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