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New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

Most, if not all, cytokines activate phosphatidylinositol 3-kinase (PI-3K). Although many cytokine receptors have direct binding sites for the p85 subunit of PI-3K, others, such as the interleukin-3 (IL-3) receptor beta common chain (βc) and the IL-2 receptor beta chain (IL-2Rβ), lack such sites, le...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Gu, Haihua, Maeda, Hiroyuki, Moon, James J., Lord, James D., Yoakim, Monique, Nelson, Brad H., Neel, Benjamin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2000
Schlagworte:
Cell Growth and Development
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.19.7109-7120.2000
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