The Shc-binding site of the β(c) subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis

Lignende værker

• Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.
  af: Woodcock, J M, et al.
  Udgivet: (1994)
• 14-3-3:Shc Scaffolds Integrate Phosphoserine and Phosphotyrosine Signaling to Regulate Phosphatidylinositol 3-Kinase Activation and Cell Survival
  af: Barry, Emma F., et al.
  Udgivet: (2009)
• Slow-Dissociation Effect of Common Signaling Subunit β on IL5 and GM-CSF Receptor Assembly
  af: Ishino, Tetsuya, et al.
  Udgivet: (2008)
• The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities
  af: Dhagat, Urmi, et al.
  Udgivet: (2018)
• Elevated levels of GM-CSF and IL-1 in the serum, peritoneal and pleural cavities of GM-CSF transgenic mice.
  af: Gearing, A J, et al.
  Udgivet: (1989)